What is Tramadol
Tramadol is one of the most widely abused drugs in North America and Worldwide. Addiction is nothing now, but what is new is the super worrying trend of increasing deaths due to Tramadol overdose. In part, this can be said to be due to a number of factors such as:
- Lack of education around Tramadol
- Increase in Pharmaceutical Prescriptions generally
- A failure of Governments worldwide to do enough to stop Tramadol addiction and related deaths
- Societal thinking regarding addicts and Tramadol addiction
- Lack of Harm Reduction methods around Tramadol usage
- Lack of addiction related education in the medical professional
Further reading about Tramadol from around the web
Tramadol, sold under the brand name Ultram among others, is an opioid pain medication used to treat moderate to moderately severe pain. When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour. It is also available by injection. It may be sold in combination with paracetamol (acetaminophen) or as longer-acting formulations.
As is typical of opioids, common side effects include constipation, itchiness, and nausea. Serious side effects may include seizures, increased risk of serotonin syndrome, decreased alertness, and drug addiction. A change in dosage may be recommended in those with kidney or liver problems. It is not recommended in those who are at risk of suicide or in those who are pregnant. While not recommended in women who are breastfeeding, those who take a single dose should not generally stop breastfeeding. Tramadol is converted in the liver to O-desmethyltramadol (desmetramadol), an opioid with a stronger affinity to the μ-opioid receptor. Tramadol is also a serotonin–norepinephrine reuptake inhibitor (SNRI).
Tramadol was patented in 1963 and launched under the name “Tramal” in 1977 by the West German pharmaceutical company Grünenthal GmbH. In the mid-1990s, it was approved in the United Kingdom and the United States. It is available as a generic medication and marketed under many brand names worldwide. In 2018, it was the 25th most commonly prescribed medication in the United States, with more than 24 million prescriptions.