Norepinephrine and Weed
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Norepinephrine and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Norepinephrine. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Norepinephrine and Weed.
Mixing Norepinephrine and Weed
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as both a hormone and neurotransmitter. The name “noradrenaline” (from Latin ad, “near”, and ren, “kidney”) is more commonly used in the United Kingdom, whereas “norepinephrine” (from Ancient Greek ἐπῐ́ (epí), “upon”, and νεφρός (nephrós), “kidney”) is usually preferred in the United States. “Norepinephrine” is also the international nonproprietary name given to the drug. Regardless of which name is used for the substance itself, parts of the body that produce or are affected by it are referred to as noradrenergic.
The general function of norepinephrine is to mobilize the brain and body for action. Norepinephrine release is lowest during sleep, rises during wakefulness, and reaches much higher levels during situations of stress or danger, in the so-called fight-or-flight response. In the brain, norepinephrine increases arousal and alertness, promotes vigilance, enhances formation and retrieval of memory, and focuses attention; it also increases restlessness and anxiety. In the rest of the body, norepinephrine increases heart rate and blood pressure, triggers the release of glucose from energy stores, increases blood flow to skeletal muscle, reduces blood flow to the gastrointestinal system, and inhibits voiding of the bladder and gastrointestinal motility.
In the brain, noradrenaline is produced in nuclei that are small yet exert powerful effects on other brain areas. The most important of these nuclei is the locus coeruleus, located in the pons. Outside the brain, norepinephrine is used as a neurotransmitter by sympathetic ganglia located near the spinal cord or in the abdomen, as well as Merkel cells located in the skin. It is also released directly into the bloodstream by the adrenal glands. Regardless of how and where it is released, norepinephrine acts on target cells by binding to and activating adrenergic receptors located on the cell surface.
A variety of medically important drugs work by altering the actions of noradrenaline systems. Noradrenaline itself is widely used as an injectable drug for the treatment of critically low blood pressure. Beta blockers, which counter some of the effects of noradrenaline by blocking their receptors, are frequently used to treat glaucoma, migraine, and a range of cardiovascular problems. Alpha blockers, which counter a different set of noradrenaline effects, are used to treat several cardiovascular and psychiatric conditions. Alpha-2 agonists often have a sedating effect and are commonly used as anesthesia enhancers in surgery, as well as in treatment of drug or alcohol dependence. Many important psychiatric drugs exert strong effects on noradrenaline systems in the brain, resulting in side-effects that may be helpful or harmful.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Norepinephrine and Weed and an increase in anxiety.
Anyone mixing Norepinephrine and weed is likely to experience side effects. This happens with all medications whether weed or Norepinephrine is mixed with them. Side effects can be harmful when mixing Norepinephrine and weed. Doctors are likely to refuse a patient a Norepinephrine prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Norepinephrine and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Norepinephrine are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Norepinephrine. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Norepinephrine and Weed, dol not interact is wrong. There will always be an interaction between Norepinephrine and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Norepinephrine and Weed is Scromiting. This condition, reportedly caused by mixing Norepinephrine and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Norepinephrine and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Norepinephrine and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Norepinephrine?
The way in which the body absorbs and process Norepinephrine may be affected by weed. Therefore, the potency of the Norepinephrine may be less effective. Marijuana inhibits the metabolization of Norepinephrine. Not having the right potency of Norepinephrine means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Norepinephrine medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Norepinephrine medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Norepinephrine and Weed
Many individuals may not realize that there are side effects and consequences to mixing Norepinephrine and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Norepinephrine and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Norepinephrine and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Norepinephrine and Weed is not recommended.
Taking Norepinephrine and Weed together
People who take Norepinephrine and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Norepinephrine and weed depend on whether you consume more weed in relation to Norepinephrine or more Norepinephrine in relation to weed.
The use of significantly more weed and Norepinephrine will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Norepinephrine may experience effects such as:
- reduced motor reflexes from Norepinephrine and Weed
- dizziness from Weed and Norepinephrine
- nausea and vomiting due to Norepinephrine and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Norepinephrine leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Norepinephrine
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Norepinephrine this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Norepinephrine affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Norepinephrine and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Norepinephrine can be just as harmful and there is no way of knowing exactly how Norepinephrine and weed is going to affect an individual before they take it.
Taking Norepinephrine and weed together
People who take Norepinephrine and weed together will experience the effects of both substances. The use of significantly more Norepinephrine with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Norepinephrine may experience effects such as:
- reduced motor reflexes from Norepinephrine and weed
- dizziness from weed and Norepinephrine
- nausea and vomiting of the Norepinephrine
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Norepinephrine leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Norepinephrine
Taking Norepinephrine in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Norepinephrine and weed may have difficulty forming new memories. With weed vs Norepinephrine in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Norepinephrine when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Norepinephrine and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Norepinephrine Vs Weed
Studies investigating the effects of drugs such as Norepinephrine and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Norepinephrine and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Norepinephrine together.
When a small to medium amount of weed is combined with Norepinephrine, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Norepinephrine.
How long after taking Norepinephrine can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Norepinephrine has totally cleared your system before taking weed, even in small quantities.
Overdose on Norepinephrine and weed
In the case of Overdose on Norepinephrine or if you are worried after mixing Norepinephrine and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Norepinephrine or mixed weed with Norepinephrine then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Norepinephrine and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Norepinephrine and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Norepinephrine and weed. These individuals may not realize that there are side effects and consequences to consuming both Norepinephrine, marijuana and a range of antidepressants.
Studies on weed, Norepinephrine and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Norepinephrine
A lot of people suffer from depression caused by weed and Norepinephrine. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to underreporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Norepinephrine and weed
Quitting weed to take Norepinephrine
Medical professionals say an individual prescribed or taking Norepinephrine should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Norepinephrine.
A person beginning to use Norepinephrine should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Norepinephrine can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Norepinephrine may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Norepinephrine and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Norepinephrine or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Norepinephrine from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Norepinephrine.
If you take Norepinephrine, and also drink Alcohol or MDMA, you can research the effects of Norepinephrine and Alcohol , Norepinephrine and Cocaine as well as Norepinephrine and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
Norepinephrine and Weed
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