niacin and Weed
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niacin and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including niacin. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing niacin and Weed.
Mixing niacin and Weed
Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient. It can be manufactured by plants and animals from the amino acid tryptophan. Niacin is obtained in the diet from a variety of whole and processed foods, with highest contents in fortified packaged foods, meat, poultry, red fish such as tuna and salmon, lesser amounts in nuts, legumes and seeds. Niacin as a dietary supplement is used to treat pellagra, a disease caused by niacin deficiency. Signs and symptoms of pellagra include skin and mouth lesions, anemia, headaches, and tiredness. Many countries mandate its addition to wheat flour or other food grains, thereby reducing the risk of pellagra.
The amide derivative nicotinamide (niacinamide) is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP+). Although niacin and nicotinamide are identical in their vitamin activity, nicotinamide does not have the same pharmacological, lipid-modifying effects or side effects as niacin, i.e., when niacin takes on the -amide group, it does not reduce cholesterol nor cause flushing. Nicotinamide is recommended as a treatment for niacin deficiency because it can be administered in remedial amounts without causing the flushing, considered an adverse effect.
Niacin is also a prescription medication. Amounts far in excess of the recommended dietary intake for vitamin functions will lower blood triglycerides and low density lipoprotein cholesterol (LDL-C), and raise blood high density lipoprotein cholesterol (HDL-C, often referred to as “good” cholesterol). There are two forms: immediate-release and sustained-release niacin. Initial prescription amounts are 500 mg/day, increased over time until a therapeutic effect is achieved. Immediate-release doses can be as high as 3,000 mg/day; sustained-release as high as 2,000 mg/day. Despite the proven lipid changes, niacin has not been found useful for decreasing the risk of cardiovascular disease in those already on a statin. A 2010 review had concluded that niacin was effective as a mono-therapy, but a 2017 review incorporating twice as many trials concluded that prescription niacin, while affecting lipid levels, did not reduce all-cause mortality, cardiovascular mortality, myocardial infarctions, nor fatal or non-fatal strokes. Prescription niacin was shown to cause hepatotoxicity and increase risk of type 2 diabetes. Niacin prescriptions in the U.S. had peaked in 2009, at 9.4 million, declining to 1.3 million by 2017.
Niacin has the formula C
6H
5NO
2 and belongs to the group of the pyridinecarboxylic acids. As the precursor for nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate, niacin is involved in DNA repair.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between niacin and Weed and an increase in anxiety.
Anyone mixing niacin and weed is likely to experience side effects. This happens with all medications whether weed or niacin is mixed with them. Side effects can be harmful when mixing niacin and weed. Doctors are likely to refuse a patient a niacin prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of niacin and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including niacin are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of niacin. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, niacin and Weed, dol not interact is wrong. There will always be an interaction between niacin and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing niacin and Weed is Scromiting. This condition, reportedly caused by mixing niacin and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing niacin and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and niacin and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of niacin?
The way in which the body absorbs and process niacin may be affected by weed. Therefore, the potency of the niacin may be less effective. Marijuana inhibits the metabolization of niacin. Not having the right potency of niacin means a person may either have a delay in the relief of their underlying symptoms.
A person seeking niacin medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right niacin medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of niacin and Weed
Many individuals may not realize that there are side effects and consequences to mixing niacin and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix niacin and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing niacin and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of niacin and Weed is not recommended.
Taking niacin and Weed together
People who take niacin and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of niacin and weed depend on whether you consume more weed in relation to niacin or more niacin in relation to weed.
The use of significantly more weed and niacin will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and niacin may experience effects such as:
- reduced motor reflexes from niacin and Weed
- dizziness from Weed and niacin
- nausea and vomiting due to niacin and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and niacin leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and niacin
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with niacin this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and niacin affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of niacin and weed have a greater adverse effect yet leading medical recommendation is that smaller does of niacin can be just as harmful and there is no way of knowing exactly how niacin and weed is going to affect an individual before they take it.
Taking niacin and weed together
People who take niacin and weed together will experience the effects of both substances. The use of significantly more niacin with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and niacin may experience effects such as:
- reduced motor reflexes from niacin and weed
- dizziness from weed and niacin
- nausea and vomiting of the niacin
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and niacin leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs niacin
Taking niacin in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of niacin and weed may have difficulty forming new memories. With weed vs niacin in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of niacin when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of niacin and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
niacin Vs Weed
Studies investigating the effects of drugs such as niacin and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when niacin and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and niacin together.
When a small to medium amount of weed is combined with niacin, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as niacin.
How long after taking niacin can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the niacin has totally cleared your system before taking weed, even in small quantities.
Overdose on niacin and weed
In the case of Overdose on niacin or if you are worried after mixing niacin and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much niacin or mixed weed with niacin then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of niacin and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing niacin and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use niacin and weed. These individuals may not realize that there are side effects and consequences to consuming both niacin, marijuana and a range of antidepressants.
Studies on weed, niacin and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and niacin
A lot of people suffer from depression caused by weed and niacin. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to underreporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing niacin and weed
Quitting weed to take niacin
Medical professionals say an individual prescribed or taking niacin should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take niacin.
A person beginning to use niacin should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and niacin can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and niacin may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing niacin and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing niacin or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent niacin from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with niacin.
If you take niacin, and also drink Alcohol or MDMA, you can research the effects of niacin and Alcohol , niacin and Cocaine as well as niacin and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
niacin and Weed
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