moderna and Weed
Edited by Hugh Soames
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moderna and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including moderna. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing moderna and Weed.
Mixing moderna and Weed
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Moderna, Inc. ( mə-DUR-nə) is a pharmaceutical and biotechnology company based in Cambridge, Massachusetts, that focuses on RNA therapeutics, primarily mRNA vaccines. These vaccines use a copy of a molecule called messenger RNA (mRNA) to carry instructions for proteins to produce an immune response. The company’s name is derived from the terms “modified”, “RNA”, and “modern”.
The company’s only commercial product is the Moderna COVID-19 vaccine, marketed as Spikevax. The company has 45 treatment and vaccine candidates, of which 38 have entered clinical trials. Candidates include possible vaccines for influenza, HIV, respiratory syncytial virus, Epstein–Barr virus, the Nipah virus, chikungunya, human metapneumovirus, varicella zoster virus, as well as a cytomegalovirus vaccine, a Zika virus vaccine funded by the Biomedical Advanced Research and Development Authority, and three cancer vaccines. The company’s pipeline also includes a cell therapy-based treatment: a relaxin fusion protein being developed to treat acute decompensated heart failure. It also includes candidates that use OX40 ligand, interleukin 23, IL36G, and interleukin 12 for cancer immunotherapy, specifically treatment of breast cancer, urothelial carcinoma, lymphoma, and melanoma. Also being developed by Moderna is a regenerative medicine treatment that encodes vascular endothelial growth factor A to stimulate blood vessel growth for patients with myocardial ischemia.
Moderna was founded in 2010 by Derrick Rossi, Timothy A. Springer, Kenneth R. Chien, Robert S. Langer, and Noubar Afeyan. Stéphane Bancel, the current CEO, was appointed as CEO in 2011. Between 2011 and 2017, Moderna raised $2 billion in venture capital funding.
In 2013, the company formed a partnership with AstraZeneca to develop treatments for cardiovascular, metabolic, and renal diseases, as well as cancer. In January 2014, the company entered an agreement with Alexion Pharmaceuticals to develop treatments against ten diseases. On January 14, 2014, Moderna announced the creation of its first spinoff company, Onkaido Therapeutics, to focus “exclusively on developing mRNA-based oncology treatments.” It launched its second spinoff, Valera, in January 2015, with a focus on “viral, bacterial and parasitic infectious diseases.” Employees of Valera and Moderna would go on to develop an mRNA vaccine candidate against Zika virus infection. Another spinoff, Elpidera, was announced in May 2015 to continue work on RNA therapies advancing Moderna’s work with Alexion.
In 2015, the company formed a partnership with Merck & Co. to develop treatments for cancer, and in 2016 the company formed a partnership with Vertex Pharmaceuticals to develop treatments for cystic fibrosis. In January 2016, the Bill & Melinda Gates Foundation committed to provide at least $20 million in grant funding to the company.
In July 2018, the company opened a 200,000 square foot facility in Norwood, Massachusetts for manufacturing, preclinical and clinical work. In December 2018, Moderna became a public company via the largest initial public offering of a biotechnology company in history, raising $621 million by selling 27 million shares at $23 per share.
The first mRNA vaccine developed by Moderna was for influenza in 2015, and its first antibody encoded by mRNA was in 2019. In 2023, Moderna acquired OriCiro Genomics, a Japanese manufacturer of genetic engineering tools, in its first acquisition.
In early 2023, the company in collaboration with Merck won breakthrough status from the FDA for its mRNA-4157/V940 drug candidate, a cancer vaccine.
On 5 July 2023, the company announced that it entered an agreement with the Chinese government to develop mRNA drugs for exclusive use in the PRC despite political tensions between the two nations. The development of new products “would address the growing need by China to supply effective drugs to its aging population with higher rates of chronic diseases and health concerns stemming from an increasingly westernised diet”, according to the statement.
From 2020 to 2021, Moderna received $955 million from Operation Warp Speed to accelerate development of its COVID-19 vaccine, with $4.9 billion committed in total for producing 300 million vaccine doses.
In March 2020, the Food and Drug Administration approved clinical trials for the Moderna COVID‑19 vaccine candidate, and in December, the vaccine, mRNA-1273, was issued an emergency use authorization in the United States. In 2022, it gained FDA approval both for the monovalent vaccine, Spikevax, and a bivalent booster.
On February 28, 2022, Arbutus Biopharma and Genevant Sciences filed a lawsuit against Moderna, accusing the company of seven counts of patent infringement.
In April 2022, Moderna announced plans to build a $180 million vaccine factory in Montreal, forming a 10-year partnership with the Government of Canada, Quebec, and McGill University to produce 100 million Spikevax doses annually and expand vaccine research capabilities.
In August 2022, Moderna sued Pfizer and BioNTech in both Massachusetts and Germany, alleging that the Pfizer–BioNTech COVID-19 vaccine violates the patent on Moderna’s mRNA vaccine technology.
In February 2023, the company agreed to pay $400 million to the National Institutes of Health, Dartmouth College, and Scripps Research to settle a dispute over the rights to a chemical technique that was used in the vaccine.
On March 10, 2023, U.S. District Judge Mitchell Goldberg rejected a bid by Moderna to dismiss some of the patent infringement claims brought against the company by Arbutus Biopharma and Genevant Sciences.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between moderna and Weed and an increase in anxiety.
Anyone mixing moderna and weed is likely to experience side effects. This happens with all medications whether weed or moderna is mixed with them. Side effects can be harmful when mixing moderna and weed. Doctors are likely to refuse a patient a moderna prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of moderna and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including moderna are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of moderna. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, moderna and Weed, dol not interact is wrong. There will always be an interaction between moderna and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing moderna and Weed is Scromiting. This condition, reportedly caused by mixing moderna and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing moderna and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and moderna and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of moderna?
The way in which the body absorbs and process moderna may be affected by weed. Therefore, the potency of the moderna may be less effective. Marijuana inhibits the metabolization of moderna. Not having the right potency of moderna means a person may either have a delay in the relief of their underlying symptoms.
A person seeking moderna medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right moderna medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of moderna and Weed
Many individuals may not realize that there are side effects and consequences to mixing moderna and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix moderna and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing moderna and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of moderna and Weed is not recommended.
Taking moderna and Weed together
People who take moderna and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of moderna and weed depend on whether you consume more weed in relation to moderna or more moderna in relation to weed.
The use of significantly more weed and moderna will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and moderna may experience effects such as:
- reduced motor reflexes from moderna and Weed
- dizziness from Weed and moderna
- nausea and vomiting due to moderna and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and moderna leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and moderna
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with moderna this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and moderna affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of moderna and weed have a greater adverse effect yet leading medical recommendation is that smaller does of moderna can be just as harmful and there is no way of knowing exactly how moderna and weed is going to affect an individual before they take it.
Taking moderna and weed together
People who take moderna and weed together will experience the effects of both substances. The use of significantly more moderna with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and moderna may experience effects such as:
- reduced motor reflexes from moderna and weed
- dizziness from weed and moderna
- nausea and vomiting of the moderna
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and moderna leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs moderna
Taking moderna in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of moderna and weed may have difficulty forming new memories. With weed vs moderna in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of moderna when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of moderna and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
moderna Vs Weed
Studies investigating the effects of drugs such as moderna and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when moderna and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and moderna together.
When a small to medium amount of weed is combined with moderna, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as moderna.
How long after taking moderna can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the moderna has totally cleared your system before taking weed, even in small quantities.
Overdose on moderna and weed
In the case of Overdose on moderna or if you are worried after mixing moderna and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much moderna or mixed weed with moderna then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of moderna and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing moderna and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use moderna and weed. These individuals may not realize that there are side effects and consequences to consuming both moderna, marijuana and a range of antidepressants.
Studies on weed, moderna and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and moderna
A lot of people suffer from depression caused by weed and moderna. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing moderna and weed
Quitting weed to take moderna
Medical professionals say an individual prescribed or taking moderna should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take moderna.
A person beginning to use moderna should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and moderna can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and moderna may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing moderna and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing moderna or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent moderna from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with moderna.
If you take moderna, and also drink Alcohol or MDMA, you can research the effects of moderna and Alcohol , moderna and Cocaine as well as moderna and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
moderna and Weed
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