Methamphetamine and Weed

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Methamphetamine and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Methamphetamine. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Methamphetamine and Weed.
Mixing Methamphetamine and Weed
Methamphetamine (contracted from N-methylamphetamine) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. Methamphetamine was discovered in 1893 and exists as two enantiomers: levo-methamphetamine and dextro-methamphetamine. Methamphetamine properly refers to a specific chemical substance, the racemic free base, which is an equal mixture of levomethamphetamine and dextromethamphetamine in their pure amine forms. It is rarely prescribed over concerns involving human neurotoxicity and potential for recreational use as an aphrodisiac and euphoriant, among other concerns, as well as the availability of safer substitute drugs with comparable treatment efficacy such as Adderall and Vyvanse. Dextromethamphetamine is a stronger CNS stimulant than levomethamphetamine.
Both racemic methamphetamine and dextromethamphetamine are illicitly trafficked and sold owing to their potential for recreational use. The highest prevalence of illegal methamphetamine use occurs in parts of Asia and Oceania, and in the United States, where racemic methamphetamine and dextromethamphetamine are classified as schedule II controlled substances. Levomethamphetamine is available as an over-the-counter (OTC) drug for use as an inhaled nasal decongestant in the United States. Internationally, the production, distribution, sale, and possession of methamphetamine is restricted or banned in many countries, due to its placement in schedule II of the United Nations Convention on Psychotropic Substances treaty. While dextromethamphetamine is a more potent drug, racemic methamphetamine is illicitly produced more often due to the relative ease of synthesis and regulatory limits of chemical precursor availability.
In low to moderate doses, methamphetamine can elevate mood, increase alertness, concentration and energy in fatigued individuals, reduce appetite, and promote weight loss. At very high doses, it can induce psychosis, breakdown of skeletal muscle, seizures and bleeding in the brain. Chronic high-dose use can precipitate unpredictable and rapid mood swings, stimulant psychosis (e.g., paranoia, hallucinations, delirium, and delusions) and violent behavior. Recreationally, methamphetamine’s ability to increase energy has been reported to lift mood and increase sexual desire to such an extent that users are able to engage in sexual activity continuously for several days while binging the drug. Methamphetamine is known to possess a high addiction liability (i.e., a high likelihood that long-term or high dose use will lead to compulsive drug use) and high dependence liability (i.e. a high likelihood that withdrawal symptoms will occur when methamphetamine use ceases). Withdrawal from methamphetamine after heavy use may lead to a post-acute-withdrawal syndrome, which can persist for months beyond the typical withdrawal period. Methamphetamine is neurotoxic to human midbrain dopaminergic neurons at high doses. Methamphetamine has been shown to have a higher affinity and, as a result, higher toxicity toward serotonergic neurons than amphetamine. Methamphetamine neurotoxicity causes adverse changes in brain structure and function, such as reductions in grey matter volume in several brain regions, as well as adverse changes in markers of metabolic integrity.
Methamphetamine belongs to the substituted phenethylamine and substituted amphetamine chemical classes. It is related to the other dimethylphenethylamines as a positional isomer of these compounds, which share the common chemical formula C10H15N.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Methamphetamine and Weed and an increase in anxiety.
Anyone mixing Methamphetamine and weed is likely to experience side effects. This happens with all medications whether weed or Methamphetamine is mixed with them. Side effects can be harmful when mixing Methamphetamine and weed. Doctors are likely to refuse a patient a Methamphetamine prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Methamphetamine and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Methamphetamine are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Methamphetamine. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Methamphetamine and Weed, dol not interact is wrong. There will always be an interaction between Methamphetamine and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Methamphetamine and Weed is Scromiting. This condition, reportedly caused by mixing Methamphetamine and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Methamphetamine and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Methamphetamine and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Methamphetamine?
The way in which the body absorbs and process Methamphetamine may be affected by weed. Therefore, the potency of the Methamphetamine may be less effective. Marijuana inhibits the metabolization of Methamphetamine. Not having the right potency of Methamphetamine means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Methamphetamine medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Methamphetamine medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Methamphetamine and Weed
Many individuals may not realize that there are side effects and consequences to mixing Methamphetamine and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Methamphetamine and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Methamphetamine and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Methamphetamine and Weed is not recommended.
Taking Methamphetamine and Weed together
People who take Methamphetamine and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Methamphetamine and weed depend on whether you consume more weed in relation to Methamphetamine or more Methamphetamine in relation to weed.
The use of significantly more weed and Methamphetamine will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Methamphetamine may experience effects such as:
- reduced motor reflexes from Methamphetamine and Weed
- dizziness from Weed and Methamphetamine
- nausea and vomiting due to Methamphetamine and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Methamphetamine leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Methamphetamine
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Methamphetamine this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Methamphetamine affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Methamphetamine and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Methamphetamine can be just as harmful and there is no way of knowing exactly how Methamphetamine and weed is going to affect an individual before they take it.
Taking Methamphetamine and weed together
People who take Methamphetamine and weed together will experience the effects of both substances. The use of significantly more Methamphetamine with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Methamphetamine may experience effects such as:
- reduced motor reflexes from Methamphetamine and weed
- dizziness from weed and Methamphetamine
- nausea and vomiting of the Methamphetamine
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Methamphetamine leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Methamphetamine
Taking Methamphetamine in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Methamphetamine and weed may have difficulty forming new memories. With weed vs Methamphetamine in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Methamphetamine when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Methamphetamine and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Methamphetamine Vs Weed
Studies investigating the effects of drugs such as Methamphetamine and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Methamphetamine and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Methamphetamine together.
When a small to medium amount of weed is combined with Methamphetamine, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Methamphetamine.
How long after taking Methamphetamine can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Methamphetamine has totally cleared your system before taking weed, even in small quantities.
Overdose on Methamphetamine and weed
In the case of Overdose on Methamphetamine or if you are worried after mixing Methamphetamine and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Methamphetamine or mixed weed with Methamphetamine then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Methamphetamine and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Methamphetamine and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Methamphetamine and weed. These individuals may not realize that there are side effects and consequences to consuming both Methamphetamine, marijuana and a range of antidepressants.
Studies on weed, Methamphetamine and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Methamphetamine
A lot of people suffer from depression caused by weed and Methamphetamine. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to underreporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Methamphetamine and weed
Quitting weed to take Methamphetamine
Medical professionals say an individual prescribed or taking Methamphetamine should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Methamphetamine.
A person beginning to use Methamphetamine should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Methamphetamine can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Methamphetamine may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Methamphetamine and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Methamphetamine or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Methamphetamine from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Methamphetamine.
If you take Methamphetamine, and also drink Alcohol or MDMA, you can research the effects of Methamphetamine and Alcohol , Methamphetamine and Cocaine as well as Methamphetamine and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.

Methamphetamine and Weed
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