Loperamide Withdrawal

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Loperamide Withdrawal

Authored by Philippa Gold Edited by Hugh Soames


Must Read Disclaimer: We use fact-based content and publish material that is researched, cited, edited and reviewed by professionals. The information we publish is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.


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Loperamide Withdrawal


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Loperamide Withdrawal

What is Loperamide


Loperamide is one of the most widely abused drugs in North America and Worldwide. Addiction is nothing now, but what is new is the super worrying trend of increasing deaths due to Loperamide overdose. In part, this can be said to be due to a number of factors such as:


  • Lack of education around Loperamide
  • Increase in Pharmaceutical Prescriptions generally
  • A failure of Governments worldwide to do enough to stop Loperamide addiction and related deaths
  • Societal thinking regarding addicts and Loperamide addiction
  • Lack of Harm Reduction methods around Loperamide usage
  • Lack of addiction related education in the medical professional


Further reading about Loperamide from around the web

Loperamide, sold under the brand name Imodium, among others, is a medication of the opioid receptor agonist class used to decrease the frequency of diarrhea. It is often used for this purpose in irritable bowel syndrome, inflammatory bowel disease and short bowel syndrome. It is not recommended for those with blood in the stool, mucus in the stool, or fevers. The medication is taken by mouth.

Common side effects include abdominal pain, constipation, sleepiness, vomiting, and a dry mouth. It may increase the risk of toxic megacolon. Loperamide’s safety in pregnancy is unclear, but no evidence of harm has been found. It appears to be safe in breastfeeding. It is an opioid with no significant absorption from the gut and does not cross the blood–brain barrier when used at normal doses. It works by slowing the contractions of the intestines.

beat withdrawal symptoms

beat withdrawal symptoms of Loperamide

What Are Loperamide Withdrawal Symptoms?


Withdrawal from Loperamide is a serious matter. The effects on the body from Loperamide use is extreme, and because of these effects Loperamide withdrawal can very quickly become an acute medical emergency. Withdrawal from Loperamide can cause a hypertensive crisis or myocardial infraction. In other words, a stroke or heart attack caused by sudden stoppage in taking Loperamide or respiratory distress syndrome whereby your body shuts down from the lungs and respiratory system outwards.  Loperamide withdrawal can also lead to serious anxiety and mental health related issues.


Never in any circumstances underestimate the seriousness of Loperamide withdrawal1https://pubmed.ncbi.nlm.nih.gov/2891684/. If you are withdrawing from Loperamide it is advisable to seek medical attention and in the case of medical emergency from Loperamide withdrawal do not hesitate to head to the nearest Emergency Room.


Loperamide withdrawal will vary for everyone and will be affected by several factors. The length and severity of Loperamide use with be one of the main predictors of withdrawal symptoms and intensity. With Loperamide withdrawal, it’s impossible to accurately predict how an individual will react to withdrawal.


Loperamide Withdrawal Timeline


Full Loperamide withdrawal often takes seven to fourteen days but sometimes longer, and the Loperamide withdrawal symptoms are categorized according to their severity.


There are no minor symptoms of Loperamide withdrawal. The first symptoms to exhibit themselves, usually 3-12 hours after Loperamide withdrawal starts proper are headaches, tremors, sweating, itching, nausea, vomiting, diarrhea, fever and total confusion with anxiety or depression.


These are followed relatively quickly by the next stage in Loperamide withdrawal timeline by:


  • Insomnia
  • Seizures
  • Hallucinations
  • Confusion
  • Tremors
  • Anxiety
  • Digestive discomfort
  • Headaches
  • Heart palpitations
  • Panic attacks
  • Muscle pain
  • Psychosis
  • Delirium tremens
  • Relapse


Worryingly, every time an individual attempts Loperamide withdrawal the severity of symptoms tends to increase.


Loperamide withdrawal has a mortality rate of between three and 19 per cent, depending on seriousness of Loperamide usage.


Withdrawal from Loperamide is a physically demanding process, in which the body will utilize every means possible to remove toxins, while creating psychological challenges because of the changes to the individuals brain chemistry.


Loperamide Detox Process


The severity of Loperamide detox makes it a process that should be approached carefully. Loperamide Detox, especially for those with a heavy or long-lasting Loperamide dependency, produces a range of symptoms and in extreme cases withdrawal can be fatal. However much they may want to end their addiction to Loperamide, it’s vital to seek medical advice and enlist the support of their loved ones.


Loperamide Withdrawal at a Rehab


Detoxing from Loperamide within a treatment facility ensures medical help if it’s needed during the treatment process. Because Loperamide rebound is a significant danger during withdrawal, having medical personnel present 24-hours a day can mean an instant response to any hypertensive or life-threatening crisis that may occur as a professional tapering process lowers the chances of patients experiencing fatal episodes.


Loperamide withdrawal and detox begins with an initial medical exam to determine the patient’s physical condition upon entry into the rehab. This pre-detox Loperamide withdrawal period can last up to 24 hours, as medical personnel determines both the patient’s general medical condition and drug history.


Detoxification of the patient’s body from Loperamide begins after the pre-detox period ends. Medically assisted or tapered withdrawal from Loperamide can take up to a few weeks to complete.

Rapid Detox from Loperamide


Rapid detox from Loperamide is a controversial topic and one that is unlikely to be accepted by everyone for its positive uses. It is a concept that has helped individuals addicted to Loperamide and other drugs kick the habit and gain the help they need to live a healthier lifestyle.


A patient undergoing a rapid detox from Loperamide is put under anesthesia for up to six hours. During this time, an opioid antagonist drug such as naltrexone is used to remove the Loperamide from the patient’s body. Rapid detox can alleviate some of the more distressing symptoms of Loperamide withdrawal.


The Loperamide rapid detox method is used to stop a patient from feeling the devastating effects of Loperamide withdrawal. Sedating the patient and putting them under anaesthesia allows them to “sleep” through the initial heavy Loperamide withdrawal and detox process. The hope is that after the rapid detox process, the patient will wake up with their body completely clean of Loperamide. The remainder of the withdrawal process will be minimal enabling the person to get on with the rehab process. Throughout rapid detox, the patient is monitored to ensure safety.


Does Loperamide Rapid Detox Help Withdrawal Symptoms?


Experts claim that rapid detox from Loperamide is a safe way to cleanse the body. It is also more pleasant as individuals who go through Loperamide withdrawal can experience shakes, sweats, nausea, and other issues for long periods.


Loperamide withdrawal can take weeks to fully complete. However, rapid detox from Loperamide can take only a few days to a week at most. While the process of undergoing anaesthesia is just a few hours, Loperamide detox patients can be kept in a medical clinic for monitoring afterwards. The process enables a patient to get – for many – the most difficult and frightening part of rehab out of the way. Once completed, patients can focus on the mental and emotional side of recovery.


For most Loperamide addicts, the biggest barrier of attending rehab is withdrawal. The pain and distress Loperamide withdrawal can have on a person can drive them back to using. Therefore, limiting or stopping a person’s physical Loperamide withdrawal symptoms allows them to focus on making a full recovery.


By completing a residential rehab program following rapid detox, individuals can fully recover from their Loperamide addiction.

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