clotrimazole and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
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What happens when you mix clotrimazole and alcohol


Side effects of mixing alcohol and clotrimazole can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect clotrimazole and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix clotrimazole and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing clotrimazole and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and clotrimazole


Alcohol and clotrimazole creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and clotrimazole and even mixing a small amount of clotrimazole and alcohol is not recommended.


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Mixing alcohol and clotrimazole


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with clotrimazole this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and clotrimazole affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of clotrimazole and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how clotrimazole and alcohol is going to affect an individual before they take it.


Taking clotrimazole and alcohol together


People who take alcohol and clotrimazole together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of clotrimazole and alcohol depend on whether you consume more alcohol in relation to clotrimazole or more clotrimazole in relation to alcohol.


The use of significantly more clotrimazole with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and clotrimazole may experience effects such as:


  • reduced motor reflexes from alcohol and clotrimazole
  • dizziness from alcohol and clotrimazole
  • nausea and vomiting of the clotrimazole


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and clotrimazole leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs clotrimazole


Taking clotrimazole in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of clotrimazole and alcohol may have difficulty forming new memories. With alcohol vs clotrimazole in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of clotrimazole when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of clotrimazole and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping clotrimazole can also cause withdrawals.


clotrimazole Vs alcohol


Studies investigating the effects of drugs such as clotrimazole and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when clotrimazole and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and clotrimazole together.


When a small to medium amount of alcohol is combined with clotrimazole, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as clotrimazole.


clotrimazole and alcohol


Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete’s foot and jock itch. It can be taken by mouth or applied as a cream to the skin or in the vagina.

Common side effects when taken by mouth include nausea and itchiness. When applied to the skin, common side effects include redness and a burning sensation. In pregnancy, use on the skin or in the vagina is believed to be safe. There is no evidence of harm when used by mouth during pregnancy but this has been less well studied. When used by mouth, greater care should be taken in those with liver problems. It is in the azole class of medications and works by disrupting the fungal cell membrane.



How long after taking clotrimazole can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the clotrimazole has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on clotrimazole and alcohol


Overdose on clotrimazole and alcohol is alarmingly common and can often be fatal. In the case of Overdose on clotrimazole or if you are worried after mixing clotrimazole and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much clotrimazole or mixed alcohol with clotrimazole then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of clotrimazole and alcohol. The combination of alcohol and clotrimazole increases the likelihood that a person would be transferred to intensive care.


If you take clotrimazole, and also smoke weed or take MDMA, you can research the effects of clotrimazole and weed , clotrimazole and Cocaine as well as clotrimazole and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

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If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


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clotrimazole and Alcohol

clotrimazole and Alcohol

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