clopidogrel and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
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What happens when you mix clopidogrel and alcohol


Side effects of mixing alcohol and clopidogrel can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect clopidogrel and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix clopidogrel and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing clopidogrel and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and clopidogrel


Alcohol and clopidogrel creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and clopidogrel and even mixing a small amount of clopidogrel and alcohol is not recommended.


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Mixing alcohol and clopidogrel


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with clopidogrel this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and clopidogrel affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of clopidogrel and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how clopidogrel and alcohol is going to affect an individual before they take it.


Taking clopidogrel and alcohol together


People who take alcohol and clopidogrel together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of clopidogrel and alcohol depend on whether you consume more alcohol in relation to clopidogrel or more clopidogrel in relation to alcohol.


The use of significantly more clopidogrel with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and clopidogrel may experience effects such as:


  • reduced motor reflexes from alcohol and clopidogrel
  • dizziness from alcohol and clopidogrel
  • nausea and vomiting of the clopidogrel


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and clopidogrel leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs clopidogrel


Taking clopidogrel in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of clopidogrel and alcohol may have difficulty forming new memories. With alcohol vs clopidogrel in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of clopidogrel when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of clopidogrel and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping clopidogrel can also cause withdrawals.


clopidogrel Vs alcohol


Studies investigating the effects of drugs such as clopidogrel and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when clopidogrel and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and clopidogrel together.


When a small to medium amount of alcohol is combined with clopidogrel, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as clopidogrel.


clopidogrel and alcohol


Clopidogrel — sold under the brand name Plavix, among others — is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy). It is taken by mouth. Its effect starts about two hours after intake and lasts for five days.

Common side effects include headache, nausea, easy bruising, itching, and heartburn. More severe side effects include bleeding and thrombotic thrombocytopenic purpura. While there is no evidence of harm from use during pregnancy, such use has not been well studied. Clopidogrel is in the thienopyridine-class of antiplatelets. It works by irreversibly inhibiting a receptor called P2Y12 on platelets.



How long after taking clopidogrel can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the clopidogrel has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on clopidogrel and alcohol


Overdose on clopidogrel and alcohol is alarmingly common and can often be fatal. In the case of Overdose on clopidogrel or if you are worried after mixing clopidogrel and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much clopidogrel or mixed alcohol with clopidogrel then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of clopidogrel and alcohol. The combination of alcohol and clopidogrel increases the likelihood that a person would be transferred to intensive care.


If you take clopidogrel, and also smoke weed or take MDMA, you can research the effects of clopidogrel and weed , clopidogrel and Cocaine as well as clopidogrel and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

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If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


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clopidogrel and Alcohol

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