Chlorothiazide and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
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What happens when you mix Chlorothiazide and alcohol


Side effects of mixing alcohol and Chlorothiazide can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect Chlorothiazide and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Chlorothiazide and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Chlorothiazide and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and Chlorothiazide


Alcohol and Chlorothiazide creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and Chlorothiazide and even mixing a small amount of Chlorothiazide and alcohol is not recommended.


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Mixing alcohol and Chlorothiazide


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with Chlorothiazide this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and Chlorothiazide affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Chlorothiazide and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how Chlorothiazide and alcohol is going to affect an individual before they take it.


Taking Chlorothiazide and alcohol together


People who take alcohol and Chlorothiazide together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Chlorothiazide and alcohol depend on whether you consume more alcohol in relation to Chlorothiazide or more Chlorothiazide in relation to alcohol.


The use of significantly more Chlorothiazide with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and Chlorothiazide may experience effects such as:


  • reduced motor reflexes from alcohol and Chlorothiazide
  • dizziness from alcohol and Chlorothiazide
  • nausea and vomiting of the Chlorothiazide


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and Chlorothiazide leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs Chlorothiazide


Taking Chlorothiazide in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Chlorothiazide and alcohol may have difficulty forming new memories. With alcohol vs Chlorothiazide in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Chlorothiazide when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Chlorothiazide and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping Chlorothiazide can also cause withdrawals.


Chlorothiazide Vs alcohol


Studies investigating the effects of drugs such as Chlorothiazide and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Chlorothiazide and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and Chlorothiazide together.


When a small to medium amount of alcohol is combined with Chlorothiazide, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as Chlorothiazide.


Chlorothiazide and alcohol


Chlorothiazide, sold under the brand name Diuril among others, is an organic compound used as a diuretic and as an antihypertensive.

It is used both within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. Most often taken in pill form, it is usually taken orally once or twice a day. In the ICU setting, chlorothiazide is given to diurese a patient in addition to furosemide (Lasix). Working in a separate mechanism from furosemide and absorbed enterically as a reconstituted suspension administered through a nasogastric tube (NG tube), the two drugs potentiate one another.



How long after taking Chlorothiazide can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the Chlorothiazide has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on Chlorothiazide and alcohol


Overdose on Chlorothiazide and alcohol is alarmingly common and can often be fatal. In the case of Overdose on Chlorothiazide or if you are worried after mixing Chlorothiazide and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much Chlorothiazide or mixed alcohol with Chlorothiazide then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Chlorothiazide and alcohol. The combination of alcohol and Chlorothiazide increases the likelihood that a person would be transferred to intensive care.


If you take Chlorothiazide, and also smoke weed or take MDMA, you can research the effects of Chlorothiazide and weed , Chlorothiazide and Cocaine as well as Chlorothiazide and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

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If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


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Chlorothiazide and Alcohol

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