carafate and Weed
Edited by Hugh Soames
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carafate and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including carafate. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing carafate and Weed.
Mixing carafate and Weed
Sucralfate, sold under various brand names, is a medication used to treat stomach ulcers, gastroesophageal reflux disease (GERD), radiation proctitis, and stomach inflammation and to prevent stress ulcers. Its usefulness in people infected by H. pylori is limited. It is used by mouth (for upper GIT ulcers) and rectally (for radiation proctitis).
Common side effects include constipation. Serious side effects may include bezoar formation and encephalopathy. Use appears to be safe in pregnancy and breastfeeding. How it works is unclear but is believed to involve binding to the ulcer and protecting it from further damage.
Sucralfate was approved for medical use in the United States in 1981. It is available as a generic medication. In 2020, it was the 182nd most commonly prescribed medication in the United States, with more than 2 million prescriptions.
Sucralfate is used for the treatment of active duodenal ulcers not related to the use of nonsteroidal anti-inflammatory drugs (NSAIDs), as the mechanism behind these ulcers is due to acid oversecretion. It is not FDA approved for gastric ulcers, but is widely used because of evidence of efficacy. The use for sucralfate in peptic ulcer disease has diminished recently, but it is still the preferred agent for stress ulcer prevention.
Sucralfate has also been used for the following conditions:
The most common side effect seen is constipation (2-3%). Less commonly reported side effects (<0.5%) include flatulence, headache, hypophosphatemia, xerostomia (dry mouth), and bezoar formation.
Use of this drug is not recommended for people with chronic kidney failure, as it might cause aluminium accumulation and toxicity.
A few well-controlled studies have been carried out investigating the safety and efficacy of sucralfate in children and pregnant women (Pregnancy Category B).
Sucralfate is a locally acting substance that in an acidic environment (pH < 4) reacts with hydrochloric acid in the stomach to form a cross-linking, viscous, paste-like material capable of acting as an acid buffer for as long as 6 to 8 hours after a single dose. It also attaches to proteins on the surface of ulcers, such as albumin and fibrinogen, to form stable insoluble complexes. These complexes serve as protective barriers at the ulcer surface, preventing further damage from acid, pepsin, and bile. In addition, sucralfate prevents back diffusion of hydrogen ions, and adsorbs both pepsin and bile acids.
It has been thought that sucralfate also stimulates the production of prostaglandin E2, epidermal growth factors (EGF), bFGF, and gastric mucus.
Brand names include Carafate in U.S.A., Sucramal in Italy, Sucrafil, Sufrate, Sucralpro, Sucralcoat, Pepsigard, Sucral, Hapifate, Sucralpro in India, Sutra or Musin in parts of South-East Asia, Sulcrate in Canada, Discral (sucralfato) in México, Ulsanic in South Africa and Israel, Andapsin in Sweden and Antepsin. Sucracell in India.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between carafate and Weed and an increase in anxiety.
Anyone mixing carafate and weed is likely to experience side effects. This happens with all medications whether weed or carafate is mixed with them. Side effects can be harmful when mixing carafate and weed. Doctors are likely to refuse a patient a carafate prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of carafate and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including carafate are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of carafate. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, carafate and Weed, dol not interact is wrong. There will always be an interaction between carafate and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing carafate and Weed is Scromiting. This condition, reportedly caused by mixing carafate and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing carafate and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and carafate and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of carafate?
The way in which the body absorbs and process carafate may be affected by weed. Therefore, the potency of the carafate may be less effective. Marijuana inhibits the metabolization of carafate. Not having the right potency of carafate means a person may either have a delay in the relief of their underlying symptoms.
A person seeking carafate medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right carafate medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of carafate and Weed
Many individuals may not realize that there are side effects and consequences to mixing carafate and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix carafate and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing carafate and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of carafate and Weed is not recommended.
Taking carafate and Weed together
People who take carafate and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of carafate and weed depend on whether you consume more weed in relation to carafate or more carafate in relation to weed.
The use of significantly more weed and carafate will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and carafate may experience effects such as:
- reduced motor reflexes from carafate and Weed
- dizziness from Weed and carafate
- nausea and vomiting due to carafate and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and carafate leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and carafate
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with carafate this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and carafate affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of carafate and weed have a greater adverse effect yet leading medical recommendation is that smaller does of carafate can be just as harmful and there is no way of knowing exactly how carafate and weed is going to affect an individual before they take it.
Taking carafate and weed together
People who take carafate and weed together will experience the effects of both substances. The use of significantly more carafate with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and carafate may experience effects such as:
- reduced motor reflexes from carafate and weed
- dizziness from weed and carafate
- nausea and vomiting of the carafate
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and carafate leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs carafate
Taking carafate in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of carafate and weed may have difficulty forming new memories. With weed vs carafate in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of carafate when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of carafate and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
carafate Vs Weed
Studies investigating the effects of drugs such as carafate and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when carafate and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and carafate together.
When a small to medium amount of weed is combined with carafate, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as carafate.
How long after taking carafate can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the carafate has totally cleared your system before taking weed, even in small quantities.
Overdose on carafate and weed
In the case of Overdose on carafate or if you are worried after mixing carafate and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much carafate or mixed weed with carafate then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of carafate and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing carafate and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use carafate and weed. These individuals may not realize that there are side effects and consequences to consuming both carafate, marijuana and a range of antidepressants.
Studies on weed, carafate and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and carafate
A lot of people suffer from depression caused by weed and carafate. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing carafate and weed
Quitting weed to take carafate
Medical professionals say an individual prescribed or taking carafate should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take carafate.
A person beginning to use carafate should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and carafate can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and carafate may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing carafate and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing carafate or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent carafate from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with carafate.
If you take carafate, and also drink Alcohol or MDMA, you can research the effects of carafate and Alcohol , carafate and Cocaine as well as carafate and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
carafate and Weed
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