capecitabine and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
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What happens when you mix capecitabine and alcohol


Side effects of mixing alcohol and capecitabine can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect capecitabine and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix capecitabine and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing capecitabine and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and capecitabine


Alcohol and capecitabine creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and capecitabine and even mixing a small amount of capecitabine and alcohol is not recommended.


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Mixing alcohol and capecitabine


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with capecitabine this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and capecitabine affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of capecitabine and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how capecitabine and alcohol is going to affect an individual before they take it.


Taking capecitabine and alcohol together


People who take alcohol and capecitabine together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of capecitabine and alcohol depend on whether you consume more alcohol in relation to capecitabine or more capecitabine in relation to alcohol.


The use of significantly more capecitabine with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and capecitabine may experience effects such as:


  • reduced motor reflexes from alcohol and capecitabine
  • dizziness from alcohol and capecitabine
  • nausea and vomiting of the capecitabine


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and capecitabine leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs capecitabine


Taking capecitabine in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of capecitabine and alcohol may have difficulty forming new memories. With alcohol vs capecitabine in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of capecitabine when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of capecitabine and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping capecitabine can also cause withdrawals.


capecitabine Vs alcohol


Studies investigating the effects of drugs such as capecitabine and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when capecitabine and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and capecitabine together.


When a small to medium amount of alcohol is combined with capecitabine, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as capecitabine.


capecitabine and alcohol


Capecitabine, sold under the brand name Xeloda among others, is a anticancer medication used to treat breast cancer, gastric cancer and colorectal cancer. For breast cancer it is often used together with docetaxel. It is taken by mouth.

Common side effects include abdominal pain, vomiting, diarrhea, weakness, and rashes. Other severe side effects include blood clotting problems, allergic reactions, heart problems such as cardiomyopathy, and low blood cell counts. Use during pregnancy may result in harm to the fetus. Capecitabine, inside the body, is converted to 5-fluorouracil (5-FU) through which it acts. It belongs to the class of medications known as fluoropyrimidines, which also includes 5-FU and tegafur.



How long after taking capecitabine can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the capecitabine has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on capecitabine and alcohol


Overdose on capecitabine and alcohol is alarmingly common and can often be fatal. In the case of Overdose on capecitabine or if you are worried after mixing capecitabine and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much capecitabine or mixed alcohol with capecitabine then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of capecitabine and alcohol. The combination of alcohol and capecitabine increases the likelihood that a person would be transferred to intensive care.


If you take capecitabine, and also smoke weed or take MDMA, you can research the effects of capecitabine and weed , capecitabine and Cocaine as well as capecitabine and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

To find information on Drug rehab and addiction treatment all over the world

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If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


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