budesonide and Weed
Edited by Hugh Soames
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budesonide and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including budesonide. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing budesonide and Weed.
Mixing budesonide and Weed
Budesonide, sold under the brand name Pulmicort among others, is a medication of the corticosteroid type. It is available as an inhaler, nebulization solution, pill, nasal spray, and rectal forms. The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease (COPD). The nasal spray is used for allergic rhinitis and nasal polyps. The pills in a delayed release form and rectal forms may be used for inflammatory bowel disease including Crohn’s disease, ulcerative colitis, and microscopic colitis.
Common side effects with the inhaled form include respiratory infections, cough, and headaches. Common side effects with the pills include feeling tired, vomiting, and joint pains. Serious side effects include an increased risk of infection, loss of bone strength, and cataracts. Long-term use of the pill form may cause adrenal insufficiency. Stopping the pills suddenly following long-term use may therefore be dangerous. The inhaled form is generally safe in pregnancy. Budesonide chiefly acts as a glucocorticoid.
Budesonide was initially patented in 1973. Commercial use as an asthma medication began in 1981. It is on the World Health Organization’s List of Essential Medicines. Some forms are available as a generic medication. In 2019, generic budesonide was listed as being involved in Teva’s price fixing scheme in the United States. In 2020, it was the 207th most commonly prescribed medication in the United States, with more than 2 million prescriptions.
Budesonide is given by metered-dose inhaler or nebulizer for maintenance and prophylactic treatment of asthma, including patients who require oral corticosteroids and those who may benefit from a systemic dose reduction.
Formulations of delayed-release budesonide are an effective treatment for mild-to-moderately active Crohn’s disease involving the ileum and/or ascending colon. A Cochrane review found evidence for up to three months (but not longer) of maintenance of remission in Crohn’s disease.
Budesonide assists in the induction of remission in people with active ulcerative colitis.
Budesonide is highly effective and recommended as the drug of choice in microscopic colitis, for induction and maintenance of remission, and for both the lymphocytic colitis and collagenous colitis forms.
Budesonide in the form of nasal sprays is a treatment for allergic rhinitis.
Topical budesonide has considerable effects in eosinophilic esophagitis. For this use, it is formulated as a tablet that disperses in the mouth, and sold under the brand name Jorveza.
Budesonide (Tarpeyo (US); Kinpeygo (EU, UK)) is indicated to reduce proteinuria (increased protein levels in the urine) in adults with primary immunoglobulin A (IgA) nephropathy (Berger’s disease) at risk of rapid disease progression.
Nasal budesonide inhalers have been associated with a number of side effects. These include nose irritation or burning, bleeding or sores in the nose, lightheadedness, upset stomach, cough, hoarseness, dry mouth, rash, sore throat, bad taste in mouth, change in mucus, and blurred vision. Other symptoms which should be reported immediately include difficulty in breathing, swelling of the face, white patches in the throat, mouth, or nose, irregular menstrual periods, severe acne, and on rare occasions, behavioral changes (mostly affecting children)
Budesonide is contraindicated as a primary treatment of status asthmaticus or other acute episode of asthma where intensive measures are required. It is also contraindicated for patients who have hypersensitivity to budesonide.
Those taking tablets or capsules orally should avoid grapefruit and grapefruit juice and echinacea.: 160
Also, high-fat meals delay absorption but do not impede absorption.
Budesonide is an agonist of glucocorticoid receptors. Among its effects are:
Budesonide, also known as 11β,21-dihydroxy-16α,17α-(butylidenebis(oxy))pregna-1,4-diene-3,20-dione, is a synthetic pregnane steroid and non-halogenated cyclic ketal corticosteroid. It is the C16α hydroxyl, C16α,17α cyclic ketal with butyraldehyde derivative of prednisolone (11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione).
On 19 May 2022, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion, recommending the granting of a conditional marketing authorization for the medicinal product Kinpeygo, intended for the treatment of primary immunoglobulin A nephropathy. The applicant for this medicinal product is Calliditas Therapeutics AB. Kinpeygo is a hybrid medicine of Entocort which has been authorised in the EU since 2 April 1992. Kinpeygo contains the same active substance as Entocort but has a different formulation and a different indication. Kinpeygo was approved for medical use in the European Union in July 2022.
Aeronide (TH); Aquacort (DE); B Cort (CO); Bronex (PH); Budair (MY); Budecort DP (MY); Budenofalk (DE, GB, HK, KP, PH, SG); Budeson (AR); Budeson Aqua (AR); BudeSpray (TH); Budiair (KP); Budicort Respules (IL); Budinide (KSA); Bunase (TH); Clebudan (CN); Cortiment (CA, GB, AU); Cycortide (HK); Denecort (PH); Duasma (TW); Eltair (MY); Entocort (AR, AT, BE, BR, CH, CZ, DK, FI, FR, GB, HK, IE, IL, IT, KP, NL, NO, PL, PT, SE, TR);: 13 Giona Easyhaler (MY, SG, TH); Inflammide (PE); Miflonid (CZ); Miflonide (BE, DE, IL, IT, NZ, PT); Neumocort (PY); Novopulmon (DE, FR); Pulmicon Susp for Nebulizer (KP); Pulmicort (AT, BE, BG, BR, CH, CL, CN, CO, CR, CZ, DE, DK, DO, EE, FI, FR, GB, GR, GT, HN, HR, ID, IN, NI, NL, NO, PA, PK, PL, PT, RU, SE, SV, TR, TW, UY, VE, ZA);: 13 Pulmicort Nasal Turbohaler (CL, KE, MU, NG); Pulmicort Turbuhaler (KE, MU, NG); Rafton (FR); Rhinocort (AU); Rhinocort Aqua (HK); Rhinoside (GR); Symbicort (FR, UK, US, ZA) Uceris (US).
Budesonide was recommended in April 2021 by the UK’s NHS to treat COVID-19 on a case-by-case basis for those aged 50 years of age and older. After a University of Oxford research team found in a trial with 1,700 patients that budesonide could benefit many people over 50 with COVID-19 symptoms, it was recommended from 12 April 2021, by the National Health Service in the UK for general practitioners (GPs) to treat COVID-19 on a case-by-case basis. Results of a large-scale trial published in August 2021 suggest that inhaled budesonide improves the time of recovery and people’s well-being during the recovery process. Inhalational budesonide was added to the recommended treatment for cases of COVID-19 in India in April 2021. The NIH recommendation was withdrawn in December 2021 citing the need for more research.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between budesonide and Weed and an increase in anxiety.
Anyone mixing budesonide and weed is likely to experience side effects. This happens with all medications whether weed or budesonide is mixed with them. Side effects can be harmful when mixing budesonide and weed. Doctors are likely to refuse a patient a budesonide prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of budesonide and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including budesonide are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of budesonide. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, budesonide and Weed, dol not interact is wrong. There will always be an interaction between budesonide and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing budesonide and Weed is Scromiting. This condition, reportedly caused by mixing budesonide and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing budesonide and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and budesonide and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of budesonide?
The way in which the body absorbs and process budesonide may be affected by weed. Therefore, the potency of the budesonide may be less effective. Marijuana inhibits the metabolization of budesonide. Not having the right potency of budesonide means a person may either have a delay in the relief of their underlying symptoms.
A person seeking budesonide medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right budesonide medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of budesonide and Weed
Many individuals may not realize that there are side effects and consequences to mixing budesonide and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix budesonide and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing budesonide and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of budesonide and Weed is not recommended.
Taking budesonide and Weed together
People who take budesonide and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of budesonide and weed depend on whether you consume more weed in relation to budesonide or more budesonide in relation to weed.
The use of significantly more weed and budesonide will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and budesonide may experience effects such as:
- reduced motor reflexes from budesonide and Weed
- dizziness from Weed and budesonide
- nausea and vomiting due to budesonide and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and budesonide leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and budesonide
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with budesonide this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and budesonide affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of budesonide and weed have a greater adverse effect yet leading medical recommendation is that smaller does of budesonide can be just as harmful and there is no way of knowing exactly how budesonide and weed is going to affect an individual before they take it.
Taking budesonide and weed together
People who take budesonide and weed together will experience the effects of both substances. The use of significantly more budesonide with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and budesonide may experience effects such as:
- reduced motor reflexes from budesonide and weed
- dizziness from weed and budesonide
- nausea and vomiting of the budesonide
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and budesonide leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs budesonide
Taking budesonide in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of budesonide and weed may have difficulty forming new memories. With weed vs budesonide in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of budesonide when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of budesonide and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
budesonide Vs Weed
Studies investigating the effects of drugs such as budesonide and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when budesonide and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and budesonide together.
When a small to medium amount of weed is combined with budesonide, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as budesonide.
How long after taking budesonide can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the budesonide has totally cleared your system before taking weed, even in small quantities.
Overdose on budesonide and weed
In the case of Overdose on budesonide or if you are worried after mixing budesonide and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much budesonide or mixed weed with budesonide then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of budesonide and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing budesonide and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use budesonide and weed. These individuals may not realize that there are side effects and consequences to consuming both budesonide, marijuana and a range of antidepressants.
Studies on weed, budesonide and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and budesonide
A lot of people suffer from depression caused by weed and budesonide. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing budesonide and weed
Quitting weed to take budesonide
Medical professionals say an individual prescribed or taking budesonide should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take budesonide.
A person beginning to use budesonide should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and budesonide can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and budesonide may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing budesonide and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing budesonide or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent budesonide from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with budesonide.
If you take budesonide, and also drink Alcohol or MDMA, you can research the effects of budesonide and Alcohol , budesonide and Cocaine as well as budesonide and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
budesonide and Weed
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