Bosentan and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
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What happens when you mix Bosentan and alcohol


Side effects of mixing alcohol and Bosentan can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect Bosentan and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Bosentan and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Bosentan and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and Bosentan


Alcohol and Bosentan creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and Bosentan and even mixing a small amount of Bosentan and alcohol is not recommended.


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Mixing alcohol and Bosentan


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with Bosentan this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and Bosentan affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Bosentan and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how Bosentan and alcohol is going to affect an individual before they take it.


Taking Bosentan and alcohol together


People who take alcohol and Bosentan together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Bosentan and alcohol depend on whether you consume more alcohol in relation to Bosentan or more Bosentan in relation to alcohol.


The use of significantly more Bosentan with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and Bosentan may experience effects such as:


  • reduced motor reflexes from alcohol and Bosentan
  • dizziness from alcohol and Bosentan
  • nausea and vomiting of the Bosentan


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and Bosentan leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs Bosentan


Taking Bosentan in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Bosentan and alcohol may have difficulty forming new memories. With alcohol vs Bosentan in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Bosentan when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Bosentan and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping Bosentan can also cause withdrawals.


Bosentan Vs alcohol


Studies investigating the effects of drugs such as Bosentan and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Bosentan and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and Bosentan together.


When a small to medium amount of alcohol is combined with Bosentan, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as Bosentan.


Bosentan and alcohol


Bosentan, sold under the brand name Tracleer and Safebo among others, is a dual endothelin receptor antagonist medication used in the treatment of pulmonary artery hypertension (PAH).

Bosentan is available as film-coated tablets (62.5 mg or 125 mg) or as dispersable tablets for oral suspension (32 mg).



How long after taking Bosentan can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the Bosentan has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on Bosentan and alcohol


Overdose on Bosentan and alcohol is alarmingly common and can often be fatal. In the case of Overdose on Bosentan or if you are worried after mixing Bosentan and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much Bosentan or mixed alcohol with Bosentan then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Bosentan and alcohol. The combination of alcohol and Bosentan increases the likelihood that a person would be transferred to intensive care.


If you take Bosentan, and also smoke weed or take MDMA, you can research the effects of Bosentan and weed , Bosentan and Cocaine as well as Bosentan and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

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If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


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Bosentan and Alcohol

Bosentan and Alcohol

drinking too much alcohol?

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