Ayahuasca and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
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What happens when you mix Ayahuasca and alcohol


Side effects of mixing alcohol and Ayahuasca can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect Ayahuasca and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Ayahuasca and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Ayahuasca and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and Ayahuasca


Alcohol and Ayahuasca creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and Ayahuasca and even mixing a small amount of Ayahuasca and alcohol is not recommended.


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Mixing alcohol and Ayahuasca


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with Ayahuasca this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and Ayahuasca affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Ayahuasca and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how Ayahuasca and alcohol is going to affect an individual before they take it.


Taking Ayahuasca and alcohol together


People who take alcohol and Ayahuasca together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Ayahuasca and alcohol depend on whether you consume more alcohol in relation to Ayahuasca or more Ayahuasca in relation to alcohol.


The use of significantly more Ayahuasca with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and Ayahuasca may experience effects such as:


  • reduced motor reflexes from alcohol and Ayahuasca
  • dizziness from alcohol and Ayahuasca
  • nausea and vomiting of the Ayahuasca


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and Ayahuasca leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs Ayahuasca


Taking Ayahuasca in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Ayahuasca and alcohol may have difficulty forming new memories. With alcohol vs Ayahuasca in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Ayahuasca when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Ayahuasca and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping Ayahuasca can also cause withdrawals.


Ayahuasca Vs alcohol


Studies investigating the effects of drugs such as Ayahuasca and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Ayahuasca and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and Ayahuasca together.


When a small to medium amount of alcohol is combined with Ayahuasca, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as Ayahuasca.


Ayahuasca and alcohol


Ayahuasca is a South American psychoactive and entheogenic brewed drink traditionally used both socially and as a ceremonial or shamanic spiritual medicine among the indigenous peoples of the Amazon basin, and more recently in Western society. The tea causes altered states of consciousness often known as “psychedelic experiences” which include visual hallucinations and altered perceptions of reality.

Ayahuasca is commonly made from the Banisteriopsis caapi vine, the Psychotria viridis shrub or a substitute, and other ingredients including Justicia pectoralis, one of the Brugmansia (especially Brugmansia insignis and Brugmansia versicolor, or a hybrid breed) or Datura species, and mapacho (Nicotiana rustica).



How long after taking Ayahuasca can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the Ayahuasca has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on Ayahuasca and alcohol


Overdose on Ayahuasca and alcohol is alarmingly common and can often be fatal. In the case of Overdose on Ayahuasca or if you are worried after mixing Ayahuasca and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much Ayahuasca or mixed alcohol with Ayahuasca then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Ayahuasca and alcohol. The combination of alcohol and Ayahuasca increases the likelihood that a person would be transferred to intensive care.


If you take Ayahuasca, and also smoke weed or take MDMA, you can research the effects of Ayahuasca and weed , Ayahuasca and Cocaine as well as Ayahuasca and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

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If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


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Ayahuasca and Alcohol

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