apixaban and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
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What happens when you mix apixaban and alcohol


Side effects of mixing alcohol and apixaban can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect apixaban and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix apixaban and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing apixaban and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and apixaban


Alcohol and apixaban creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and apixaban and even mixing a small amount of apixaban and alcohol is not recommended.


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Mixing alcohol and apixaban


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with apixaban this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and apixaban affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of apixaban and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how apixaban and alcohol is going to affect an individual before they take it.


Taking apixaban and alcohol together


People who take alcohol and apixaban together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of apixaban and alcohol depend on whether you consume more alcohol in relation to apixaban or more apixaban in relation to alcohol.


The use of significantly more apixaban with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and apixaban may experience effects such as:


  • reduced motor reflexes from alcohol and apixaban
  • dizziness from alcohol and apixaban
  • nausea and vomiting of the apixaban


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and apixaban leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs apixaban


Taking apixaban in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of apixaban and alcohol may have difficulty forming new memories. With alcohol vs apixaban in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of apixaban when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of apixaban and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping apixaban can also cause withdrawals.


apixaban Vs alcohol


Studies investigating the effects of drugs such as apixaban and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when apixaban and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and apixaban together.


When a small to medium amount of alcohol is combined with apixaban, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as apixaban.


apixaban and alcohol


Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa. Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. It is used as an alternative to warfarin and does not require monitoring by blood tests or dietary restrictions. It is taken by mouth.

Common side effects include bleeding and nausea. Other side effects may include bleeding around the spine and allergic reactions. Use is not recommended during pregnancy or breastfeeding. Use appears to be relatively safe in those with mild kidney problems. Compared to warfarin it has fewer interactions with other medications. It is a direct factor Xa inhibitor.



How long after taking apixaban can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the apixaban has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on apixaban and alcohol


Overdose on apixaban and alcohol is alarmingly common and can often be fatal. In the case of Overdose on apixaban or if you are worried after mixing apixaban and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much apixaban or mixed alcohol with apixaban then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of apixaban and alcohol. The combination of alcohol and apixaban increases the likelihood that a person would be transferred to intensive care.


If you take apixaban, and also smoke weed or take MDMA, you can research the effects of apixaban and weed , apixaban and Cocaine as well as apixaban and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

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If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


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apixaban and Alcohol

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