amoxicillin-clavulanate and Weed
Edited by Hugh Soames
Advertising: We may earn a commission if you buy anything via our advertising or external links
amoxicillin-clavulanate and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including amoxicillin-clavulanate. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing amoxicillin-clavulanate and Weed.
Mixing amoxicillin-clavulanate and Weed
Amoxicillin/clavulanic acid, also known as co-amoxiclav or amox-clav, sold under the brand name Augmentin, among others, is an antibiotic medication used for the treatment of a number of bacterial infections. It is a combination consisting of amoxicillin, a β-lactam antibiotic, and potassium clavulanate, a β-lactamase inhibitor. It is specifically used for otitis media, streptococcal pharyngitis, pneumonia, cellulitis, urinary tract infections, and animal bites. It is taken by mouth or by injection into a vein.
Common side effects include diarrhea, vomiting, and allergic reactions. It also increases the risk of yeast infections, headaches, and blood clotting problems. It is not recommended in people with a history of a penicillin allergy. It is relatively safe for use during pregnancy.
Amoxicillin/clavulanic acid was approved for medical use in the United States in 1984. It is on the World Health Organization’s List of Essential Medicines. The World Health Organization classifies amoxicillin/clavulanic-acid as critically important for human medicine. It is available as a generic medication. In 2020, it was the 107th most commonly prescribed medication in the United States, with more than 6 million prescriptions.
Amoxicillin/clavulanic acid is widely used to treat or prevent many infections caused by susceptible bacteria, such as:
It is also used for tuberculosis that is resistant to other treatments. The World Health Organization recommends giving amoxicillin-clavulanate along with meropenem as one of the therapeutic options in drug resistant tuberculosis. However, across the spectrum of dosage of amoxicillin-clavulanate combination, the dose of clavulanate is constant at 125 mg, whereas the dose of amoxicillin varies at 250 mg, 500 mg and 875 mg. Thus the use of low dose amoxicillin-clavulanate in combination with meropenem may be used in part of treatment regime for drug resistant TB and this has been demonstrated in a clinical setting also. Its efficacy is attributed not to the amoxicillin component, but to the protective action of clavulanic acid over meropenem against beta-lactamase produced by the micobacteria. Therefore, the minimum dosage of amoxicillin (250 mg) is recommended.
Possible side effects include diarrhea, vomiting, nausea, thrush, and skin rash. These do not usually require medical attention. As with all antimicrobial agents, antibiotic-associated diarrhea due to Clostridium difficile infection—sometimes leading to pseudomembranous colitis—may occur during or after treatment with amoxicillin/clavulanic acid.
Rarely, cholestatic jaundice (also referred to as cholestatic hepatitis, a form of liver toxicity) has been associated with amoxicillin/clavulanic acid. The reaction may occur up to several weeks after treatment has stopped, and usually takes weeks to resolve. It is more frequent in men, older people, and those who have taken long courses of treatment; the estimated overall incidence is one in 100,000 exposures. In the United Kingdom, co-amoxiclav carries a warning from the Committee on Safety of Medicines to this effect.
As all aminopenicillins, amoxicillin has been associated with Stevens–Johnson syndrome/toxic epidermal necrolysis, although these reactions are very rare.
British scientists working at Beecham (now part of GlaxoSmithKline), filed for patent protection for the drug combination in 1977, which was granted in 1982.
It was sold under the brand name Augmentin.
Amoxicillin/clavulanic acid is the International Nonproprietary Name (INN) and co-amoxiclav is the British Approved Name (BAN).
Many branded products indicate their strengths as the quantity of amoxicillin. Augmentin 250, for example, contains 250 mg of amoxicillin and 125 mg of clavulanic acid.
An intravenous preparation has been available in the UK since 1985, but no parenteral preparation is available in the US;[citation needed] the nearest equivalent is ampicillin/sulbactam.
Suspensions of amoxicillin/clavulanic acid are available for use in children. They must be refrigerated to maintain effectiveness.
Amoxicillin/clavulanic acid is used in numerous animals for a variety of conditions:
In combination with prednisolone, it is used for intramammary infusion for the treatment of mastitis in lactating cows. Trade names include Clavaseptin, Clavamox, and Synulox.[citation needed]
Amoxicillin/clavulanic acid is banned from use in domestic-food animals (cattle, swine, etc.) in both the US and Europe; in the UK, Synulox can be used in domestic-food animals as long as a specified withdrawal period is observed.[citation needed]
Bacterial antibiotic resistance is a growing problem in veterinary medicine. Amoxicillin/clavulanic acid is reported to be effective against clinical Klebsiella infections, but is not efficacious against Pseudomonas infections.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between amoxicillin-clavulanate and Weed and an increase in anxiety.
Anyone mixing amoxicillin-clavulanate and weed is likely to experience side effects. This happens with all medications whether weed or amoxicillin-clavulanate is mixed with them. Side effects can be harmful when mixing amoxicillin-clavulanate and weed. Doctors are likely to refuse a patient a amoxicillin-clavulanate prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of amoxicillin-clavulanate and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including amoxicillin-clavulanate are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of amoxicillin-clavulanate. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, amoxicillin-clavulanate and Weed, dol not interact is wrong. There will always be an interaction between amoxicillin-clavulanate and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing amoxicillin-clavulanate and Weed is Scromiting. This condition, reportedly caused by mixing amoxicillin-clavulanate and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing amoxicillin-clavulanate and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and amoxicillin-clavulanate and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of amoxicillin-clavulanate?
The way in which the body absorbs and process amoxicillin-clavulanate may be affected by weed. Therefore, the potency of the amoxicillin-clavulanate may be less effective. Marijuana inhibits the metabolization of amoxicillin-clavulanate. Not having the right potency of amoxicillin-clavulanate means a person may either have a delay in the relief of their underlying symptoms.
A person seeking amoxicillin-clavulanate medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right amoxicillin-clavulanate medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of amoxicillin-clavulanate and Weed
Many individuals may not realize that there are side effects and consequences to mixing amoxicillin-clavulanate and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix amoxicillin-clavulanate and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing amoxicillin-clavulanate and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of amoxicillin-clavulanate and Weed is not recommended.
Taking amoxicillin-clavulanate and Weed together
People who take amoxicillin-clavulanate and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of amoxicillin-clavulanate and weed depend on whether you consume more weed in relation to amoxicillin-clavulanate or more amoxicillin-clavulanate in relation to weed.
The use of significantly more weed and amoxicillin-clavulanate will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and amoxicillin-clavulanate may experience effects such as:
- reduced motor reflexes from amoxicillin-clavulanate and Weed
- dizziness from Weed and amoxicillin-clavulanate
- nausea and vomiting due to amoxicillin-clavulanate and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and amoxicillin-clavulanate leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and amoxicillin-clavulanate
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with amoxicillin-clavulanate this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and amoxicillin-clavulanate affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of amoxicillin-clavulanate and weed have a greater adverse effect yet leading medical recommendation is that smaller does of amoxicillin-clavulanate can be just as harmful and there is no way of knowing exactly how amoxicillin-clavulanate and weed is going to affect an individual before they take it.
Taking amoxicillin-clavulanate and weed together
People who take amoxicillin-clavulanate and weed together will experience the effects of both substances. The use of significantly more amoxicillin-clavulanate with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and amoxicillin-clavulanate may experience effects such as:
- reduced motor reflexes from amoxicillin-clavulanate and weed
- dizziness from weed and amoxicillin-clavulanate
- nausea and vomiting of the amoxicillin-clavulanate
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and amoxicillin-clavulanate leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs amoxicillin-clavulanate
Taking amoxicillin-clavulanate in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of amoxicillin-clavulanate and weed may have difficulty forming new memories. With weed vs amoxicillin-clavulanate in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of amoxicillin-clavulanate when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of amoxicillin-clavulanate and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
amoxicillin-clavulanate Vs Weed
Studies investigating the effects of drugs such as amoxicillin-clavulanate and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when amoxicillin-clavulanate and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and amoxicillin-clavulanate together.
When a small to medium amount of weed is combined with amoxicillin-clavulanate, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as amoxicillin-clavulanate.
How long after taking amoxicillin-clavulanate can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the amoxicillin-clavulanate has totally cleared your system before taking weed, even in small quantities.
Overdose on amoxicillin-clavulanate and weed
In the case of Overdose on amoxicillin-clavulanate or if you are worried after mixing amoxicillin-clavulanate and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much amoxicillin-clavulanate or mixed weed with amoxicillin-clavulanate then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of amoxicillin-clavulanate and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing amoxicillin-clavulanate and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use amoxicillin-clavulanate and weed. These individuals may not realize that there are side effects and consequences to consuming both amoxicillin-clavulanate, marijuana and a range of antidepressants.
Studies on weed, amoxicillin-clavulanate and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and amoxicillin-clavulanate
A lot of people suffer from depression caused by weed and amoxicillin-clavulanate. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing amoxicillin-clavulanate and weed
Quitting weed to take amoxicillin-clavulanate
Medical professionals say an individual prescribed or taking amoxicillin-clavulanate should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take amoxicillin-clavulanate.
A person beginning to use amoxicillin-clavulanate should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and amoxicillin-clavulanate can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and amoxicillin-clavulanate may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing amoxicillin-clavulanate and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing amoxicillin-clavulanate or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent amoxicillin-clavulanate from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with amoxicillin-clavulanate.
If you take amoxicillin-clavulanate, and also drink Alcohol or MDMA, you can research the effects of amoxicillin-clavulanate and Alcohol , amoxicillin-clavulanate and Cocaine as well as amoxicillin-clavulanate and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
amoxicillin-clavulanate and Weed
Counselling for Weed Addiction; Low Cost - Qualified Therapists - Available Now - 20% Off
We may make a commission if you purchase anything via the adverts or links on this page.
Betterhelp is for anyone suffering from mental health issues. Whether you suffer from anxiety, depression, weed addiction, eating disorders, or just need someone to speak to, Betterhelp can pair you with a qualified therapist.
In the wake of the pandemic, an increasing number of people have sought out therapeutic and conseling services to help with weed cessation. Better Help has seen a massive rise in people seeking help over the last two to three years.
If you or someone you care about is smoking or ingesting a level of weed that makes their life become unmanageable, Betterhelp has counselors and therapists on hand to help for less that $90 per week.
Specializations | Burnout, Anxiety, Depression, Stress, Anger Management, Dependencies, Grief, Seasonal Depressive Disorder, Life Crisis, Smoking Cessation, Weed Cessation (among others)
Betterhelp Cost | The standard fee for BetterHelp therapy is only $60 to $90 per week or $240 to $360 per month.
Key Takeaways |
- Largest online therapy platform
- Low cost
- Good for stopping weed
- Messaging
- Live video
- Phone calls
- Live chat
- No lock in contracts
- Cancel anytime
- Licensed and accredited therapists
Discounts Available | We have negotiated a generous 20% discount for readers of our website. Press Here to get 20% Off
