acitretin and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
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What happens when you mix acitretin and alcohol


Side effects of mixing alcohol and acitretin can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect acitretin and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix acitretin and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing acitretin and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and acitretin


Alcohol and acitretin creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and acitretin and even mixing a small amount of acitretin and alcohol is not recommended.


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Mixing alcohol and acitretin


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with acitretin this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and acitretin affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of acitretin and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how acitretin and alcohol is going to affect an individual before they take it.


Taking acitretin and alcohol together


People who take alcohol and acitretin together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of acitretin and alcohol depend on whether you consume more alcohol in relation to acitretin or more acitretin in relation to alcohol.


The use of significantly more acitretin with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and acitretin may experience effects such as:


  • reduced motor reflexes from alcohol and acitretin
  • dizziness from alcohol and acitretin
  • nausea and vomiting of the acitretin


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and acitretin leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs acitretin


Taking acitretin in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of acitretin and alcohol may have difficulty forming new memories. With alcohol vs acitretin in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of acitretin when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of acitretin and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping acitretin can also cause withdrawals.


acitretin Vs alcohol


Studies investigating the effects of drugs such as acitretin and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when acitretin and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and acitretin together.


When a small to medium amount of alcohol is combined with acitretin, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as acitretin.


acitretin and alcohol


Acitretin (trade names Soriatane and Neotigason) is a second-generation retinoid. It is taken orally, and is typically used for psoriasis.

Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments. It binds to nuclear receptors that regulates gene transcription. They induce keratinocyte differentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after two to four weeks or longer.



How long after taking acitretin can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the acitretin has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on acitretin and alcohol


Overdose on acitretin and alcohol is alarmingly common and can often be fatal. In the case of Overdose on acitretin or if you are worried after mixing acitretin and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much acitretin or mixed alcohol with acitretin then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of acitretin and alcohol. The combination of alcohol and acitretin increases the likelihood that a person would be transferred to intensive care.


If you take acitretin, and also smoke weed or take MDMA, you can research the effects of acitretin and weed , acitretin and Cocaine as well as acitretin and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

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If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


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acitretin and Alcohol

acitretin and Alcohol

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