acetominophen and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
  2. Advertising: If you buy something through our ads or external links, we may earn a commission.

What happens when you mix acetominophen and alcohol


Side effects of mixing alcohol and acetominophen can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect acetominophen and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix acetominophen and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing acetominophen and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and acetominophen


Alcohol and acetominophen creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and acetominophen and even mixing a small amount of acetominophen and alcohol is not recommended.


Addiction Counselling for Alcohol Misuse


If you or a loved one is experiencing problems with Alcohol, Compulsive behaviors or any emotional wellbeing issues we have a range of vetted Counselors and Therapists near you and online.

Mixing alcohol and acetominophen


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with acetominophen this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and acetominophen affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of acetominophen and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how acetominophen and alcohol is going to affect an individual before they take it.


Taking acetominophen and alcohol together


People who take alcohol and acetominophen together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of acetominophen and alcohol depend on whether you consume more alcohol in relation to acetominophen or more acetominophen in relation to alcohol.


The use of significantly more acetominophen with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and acetominophen may experience effects such as:


  • reduced motor reflexes from alcohol and acetominophen
  • dizziness from alcohol and acetominophen
  • nausea and vomiting of the acetominophen


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and acetominophen leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs acetominophen


Taking acetominophen in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of acetominophen and alcohol may have difficulty forming new memories. With alcohol vs acetominophen in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of acetominophen when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of acetominophen and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping acetominophen can also cause withdrawals.


acetominophen Vs alcohol


Studies investigating the effects of drugs such as acetominophen and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when acetominophen and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and acetominophen together.


When a small to medium amount of alcohol is combined with acetominophen, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as acetominophen.


acetominophen and alcohol


Paracetamol (acetaminophen or para-hydroxyacetanilide) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. It is a widely used over the counter medication and common brand names include Tylenol and Panadol.

At a standard dose, paracetamol only slightly decreases body temperature; it is inferior to ibuprofen in that respect, and the benefits of its use for fever are unclear. Paracetamol may relieve pain in acute mild migraine but only slightly in episodic tension headache. However, the aspirin/paracetamol/caffeine combination helps with both conditions where the pain is mild and is recommended as a first-line treatment for them. Paracetamol is effective for post-surgical pain, but it is inferior to ibuprofen. The paracetamol/ibuprofen combination provides further increase in potency and is superior to either drug alone. The pain relief paracetamol provides in osteoarthritis is small and clinically insignificant. The evidence in its favor for the use in low back pain, cancer pain, and neuropathic pain is insufficient.



How long after taking acetominophen can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the acetominophen has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on acetominophen and alcohol


Overdose on acetominophen and alcohol is alarmingly common and can often be fatal. In the case of Overdose on acetominophen or if you are worried after mixing acetominophen and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much acetominophen or mixed alcohol with acetominophen then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of acetominophen and alcohol. The combination of alcohol and acetominophen increases the likelihood that a person would be transferred to intensive care.


If you take acetominophen, and also smoke weed or take MDMA, you can research the effects of acetominophen and weed , acetominophen and Cocaine as well as acetominophen and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

To find information on Drug rehab and addiction treatment all over the world

Worlds Best Rehab

If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


Top Locations


acetominophen and Alcohol

acetominophen and Alcohol

drinking too much alcohol?

drinking too much alcohol?



BetterHelp is one of the most well-known online therapy providers in the World. You may have heard of BetterHelp’s advertisements on podcasts, radio, or read about it online.According to the latest statistics provided by Betterhelp, the online therapy provider has nearly 2 million customers worldwide. Its client-base makes Better Help the world’s largest online therapy provider and a very popular choice.


Better Help ticks a lot of boxes for individuals seeking counseling and therapy to restore the right balance in their lives. All too often we fail to live our best life to our full potential because of things like drinking too much alcohol too regularly, mixing alcohol and acetominophen, sadness, grief, stress and burnout. The Betterhelp platform allows users to connect with therapists that can help with a variety of wellbeing concerns.

Specializations | Alcohol Use, Burnout, Anxiety, Depression, Stress, Anger Management, Alcohol, Dependencies, Grief, Seasonal Depressive Disorder, Life Crisis, Smoking Cessation (among others)


Betterhelp Cost | The standard fee for BetterHelp therapy is only $60 to $90 per week or $240 to $360 per month.


Key Takeaways |

  • Largest online therapy platform
  • Low cost
  • Messaging
  • Live video
  • Phone calls
  • Live chat
  • No lock in contracts
  • Cancel anytime
  • Licensed and accredited therapists


Discounts Available | We have negotiated a 20% discount for readers of our website. Press Here to get 20% Off