Timolide and Weed
Edited by Hugh Soames
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Timolide and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Timolide. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Timolide and Weed.
Mixing Timolide and Weed
Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. Hydrochlorothiazide is taken by mouth and may be combined with other blood pressure medications as a single pill to increase effectiveness. Hydrochlorothiazide is a thiazide medication which inhibits reabsorption of sodium and chloride ions from the distal convoluted tubules of the kidneys, causing a natriuresis. This initially increases urine volume and lowers blood volume. It is believed to reduce peripheral vascular resistance.
Potential side effects include poor kidney function, electrolyte imbalances, including low blood potassium, and, less commonly, low blood sodium, gout, high blood sugar, and feeling lightheaded with standing.
Two companies, Merck & Co. and Ciba Specialty Chemicals, state they discovered the medication which became commercially available in 1959. It is on the World Health Organization’s List of Essential Medicines. It is available as a generic drug and is relatively affordable. In 2020, it was the eleventh most commonly prescribed medication in the United States, with more than 41 million prescriptions.
Hydrochlorothiazide is used for the treatment of hypertension, congestive heart failure, symptomatic edema, diabetes insipidus, renal tubular acidosis. It is also used for the prevention of kidney stones in those who have high levels of calcium in their urine.
Multiple studies suggest hydrochlorothiazide could be used as initial monotherapy in people with primary hypertension; however, the decision should be weighed against the consequence of long-term adverse metabolic abnormalities. Doses of hydrochlorothiazide of 50 mg or less over four years reduced mortality and development of cardiovascular diseases better than high-dose hydrochlorothiazide (50 mg or more) and beta-blockers. A 2019 review supported equivalence between drug classes for initiating monotherapy in hypertension, although thiazide or thiazide-like diuretics showed better primary effectiveness and safety profiles than angiotensin-converting enzyme inhibitors and non-dihydropyridine calcium channel blockers.
Low doses (50 mg or less) of hydrochlorothiazide as first‐line therapy for hypertension were found to reduce total mortality and cardiovascular disease events over a four-year study. Hydrochlorothiazide appears be more effective than chlorthalidone in preventing heart attacks and strokes. Hydrochlorothiazide is less potent but may be more effective than chlorthalidone in reducing blood pressure. More robust studies are required to confirm which drug is superior in reducing cardiovascular events. Side effect profile for both drugs appear similar and are dose dependent.
Hydrochlorothiazide is also sometimes used to prevent osteopenia and treat hypoparathyroidism, hypercalciuria, Dent’s disease, and Ménière’s disease.
A low level of evidence, predominantly from observational studies, suggests that thiazide diuretics have a modest beneficial effect on bone mineral density and are associated with a decreased fracture risk when compared with people not taking thiazides. Thiazides decrease mineral bone loss by promoting calcium retention in the kidney, and by directly stimulating osteoblast differentiation and bone mineral formation.
The combination of fixed-dose preparation such as losartan/hydrochlorothiazide has added advantages of a more potent antihypertensive effect with additional antihypertensive efficacy at the dose of 100 mg/25 mg when compared to monotherapy.
Package inserts contain vague and inconsistent data surrounding the use of thiazide diuretics in patients with allergies to sulfa drugs, with little evidence to support these statements. A retrospective cohort study conducted by Strom et al. concluded that there is an increased risk of an allergic reaction occurring in patients with a predisposition to allergic reactions in general rather than cross reactivity from structural components of the sulfonamide-based drug. Prescribers should examine the evidence carefully and assess each patient individually, paying particular attention to their prior history of sulfonamide hypersensitivity rather than relying on drug monograph information.
There is an increased risk of non-melanoma skin cancer. In August 2020, the Australian Therapeutic Goods Administration required the Product Information (PI) and Consumer Medicine Information (CMI) for medicines containing hydrochlorothiazide to be updated to include details about an increased risk of non-melanoma skin cancer. In August 2020, the U.S. Food and Drug Administration (FDA) updated the drug label about an increased risk of non-melanoma skin cancer (basal cell skin cancer or squamous cell skin cancer).
Hydrochlorothiazide is available as a generic drug under a large number of brand names, including Apo-Hydro, Aquazide, BPZide, Dichlotride, Esidrex, Hydrochlorot, Hydrodiuril, HydroSaluric, Hypothiazid, Microzide, Oretic and many others.
To reduce pill burden and in order to reduce side effects, hydrochlorothiazide is often used in fixed-dose combinations with many other classes of antihypertensive drugs such as:
Use of hydrochlorothiazide is prohibited by the World Anti-Doping Agency for its ability to mask the use of performance-enhancing drugs.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Timolide and Weed and an increase in anxiety.
Anyone mixing Timolide and weed is likely to experience side effects. This happens with all medications whether weed or Timolide is mixed with them. Side effects can be harmful when mixing Timolide and weed. Doctors are likely to refuse a patient a Timolide prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Timolide and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Timolide are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Timolide. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Timolide and Weed, dol not interact is wrong. There will always be an interaction between Timolide and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Timolide and Weed is Scromiting. This condition, reportedly caused by mixing Timolide and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Timolide and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Timolide and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Timolide?
The way in which the body absorbs and process Timolide may be affected by weed. Therefore, the potency of the Timolide may be less effective. Marijuana inhibits the metabolization of Timolide. Not having the right potency of Timolide means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Timolide medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Timolide medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Timolide and Weed
Many individuals may not realize that there are side effects and consequences to mixing Timolide and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Timolide and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Timolide and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Timolide and Weed is not recommended.
Taking Timolide and Weed together
People who take Timolide and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Timolide and weed depend on whether you consume more weed in relation to Timolide or more Timolide in relation to weed.
The use of significantly more weed and Timolide will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Timolide may experience effects such as:
- reduced motor reflexes from Timolide and Weed
- dizziness from Weed and Timolide
- nausea and vomiting due to Timolide and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Timolide leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Timolide
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Timolide this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Timolide affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Timolide and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Timolide can be just as harmful and there is no way of knowing exactly how Timolide and weed is going to affect an individual before they take it.
Taking Timolide and weed together
People who take Timolide and weed together will experience the effects of both substances. The use of significantly more Timolide with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Timolide may experience effects such as:
- reduced motor reflexes from Timolide and weed
- dizziness from weed and Timolide
- nausea and vomiting of the Timolide
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Timolide leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Timolide
Taking Timolide in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Timolide and weed may have difficulty forming new memories. With weed vs Timolide in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Timolide when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Timolide and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Timolide Vs Weed
Studies investigating the effects of drugs such as Timolide and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Timolide and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Timolide together.
When a small to medium amount of weed is combined with Timolide, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Timolide.
How long after taking Timolide can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Timolide has totally cleared your system before taking weed, even in small quantities.
Overdose on Timolide and weed
In the case of Overdose on Timolide or if you are worried after mixing Timolide and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Timolide or mixed weed with Timolide then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Timolide and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Timolide and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Timolide and weed. These individuals may not realize that there are side effects and consequences to consuming both Timolide, marijuana and a range of antidepressants.
Studies on weed, Timolide and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Timolide
A lot of people suffer from depression caused by weed and Timolide. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Timolide and weed
Quitting weed to take Timolide
Medical professionals say an individual prescribed or taking Timolide should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Timolide.
A person beginning to use Timolide should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Timolide can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Timolide may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Timolide and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Timolide or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Timolide from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Timolide.
If you take Timolide, and also drink Alcohol or MDMA, you can research the effects of Timolide and Alcohol , Timolide and Cocaine as well as Timolide and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
Timolide and Weed
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