Piroxicam and Weed
Edited by Hugh Soames
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Piroxicam and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Piroxicam. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Piroxicam and Weed.
Mixing Piroxicam and Weed
Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class used to relieve the symptoms of painful inflammatory conditions like arthritis. Piroxicam works by preventing the production of endogenous prostaglandins which are involved in the mediation of pain, stiffness, tenderness and swelling. The medicine is available as capsules, tablets and (not in all countries) as a prescription-free gel 0.5%. It is also available in a betadex formulation, which allows a more rapid absorption of piroxicam from the digestive tract. Piroxicam is one of the few NSAIDs that can be given parenteral routes.[citation needed]
It was patented in 1968 by Pfizer and approved for medical use in 1979. It became generic in 1992, and is marketed worldwide under many brandnames.
It is used in the treatment of certain inflammatory conditions like rheumatoid and osteoarthritis, primary dysmenorrhoea, postoperative pain; and act as an analgesic, especially where there is an inflammatory component. The European Medicines Agency issued a review of its use in 2007 and recommended that its use be limited to the treatment of chronic inflammatory conditions, as it is only in these circumstances that its risk-benefit ratio proves to be favourable.
As with other NSAIDs the principal side effects include: digestive complaints like nausea, discomfort, diarrhoea and bleeds or ulceration of the stomach, as well as headache, dizziness, nervousness, depression, drowsiness, insomnia, vertigo, hearing disturbances (such as tinnitus), high blood pressure, oedema, light sensitivity, skin reactions (including, albeit rarely, Stevens–Johnson syndrome and toxic epidermal necrolysis) and rarely, kidney failure, pancreatitis, liver damage, visual disturbances, pulmonary eosinophilia and fibrosing alveolitis. Compared to other NSAIDs it is more prone to causing gastrointestinal disturbances and serious skin reactions.
In October 2020, the U.S. Food and Drug Administration (FDA) required the drug label to be updated for all nonsteroidal anti-inflammatory medications to describe the risk of kidney problems in unborn babies that result in low amniotic fluid. They recommend avoiding NSAIDs in pregnant women at 20 weeks or later in pregnancy.
Piroxicam is an NSAID and, as such, is a non-selective COX inhibitor possessing both analgesic and antipyretic properties.
Piroxicam exists as alkenol tautomer in organic solvents and as zwitterionic form in water.
The project that produced piroxicam began in 1962 at Pfizer; the first clinical trial results were reported in 1977, and the product launched in 1980 under the brand name “Feldene”. Major patents expired in 1992 and the drug is marketed worldwide under many brandnames.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Piroxicam and Weed and an increase in anxiety.
Anyone mixing Piroxicam and weed is likely to experience side effects. This happens with all medications whether weed or Piroxicam is mixed with them. Side effects can be harmful when mixing Piroxicam and weed. Doctors are likely to refuse a patient a Piroxicam prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Piroxicam and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Piroxicam are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Piroxicam. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Piroxicam and Weed, dol not interact is wrong. There will always be an interaction between Piroxicam and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Piroxicam and Weed is Scromiting. This condition, reportedly caused by mixing Piroxicam and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Piroxicam and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Piroxicam and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Piroxicam?
The way in which the body absorbs and process Piroxicam may be affected by weed. Therefore, the potency of the Piroxicam may be less effective. Marijuana inhibits the metabolization of Piroxicam. Not having the right potency of Piroxicam means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Piroxicam medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Piroxicam medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Piroxicam and Weed
Many individuals may not realize that there are side effects and consequences to mixing Piroxicam and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Piroxicam and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Piroxicam and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Piroxicam and Weed is not recommended.
Taking Piroxicam and Weed together
People who take Piroxicam and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Piroxicam and weed depend on whether you consume more weed in relation to Piroxicam or more Piroxicam in relation to weed.
The use of significantly more weed and Piroxicam will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Piroxicam may experience effects such as:
- reduced motor reflexes from Piroxicam and Weed
- dizziness from Weed and Piroxicam
- nausea and vomiting due to Piroxicam and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Piroxicam leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Piroxicam
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Piroxicam this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Piroxicam affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Piroxicam and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Piroxicam can be just as harmful and there is no way of knowing exactly how Piroxicam and weed is going to affect an individual before they take it.
Taking Piroxicam and weed together
People who take Piroxicam and weed together will experience the effects of both substances. The use of significantly more Piroxicam with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Piroxicam may experience effects such as:
- reduced motor reflexes from Piroxicam and weed
- dizziness from weed and Piroxicam
- nausea and vomiting of the Piroxicam
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Piroxicam leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Piroxicam
Taking Piroxicam in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Piroxicam and weed may have difficulty forming new memories. With weed vs Piroxicam in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Piroxicam when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Piroxicam and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Piroxicam Vs Weed
Studies investigating the effects of drugs such as Piroxicam and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Piroxicam and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Piroxicam together.
When a small to medium amount of weed is combined with Piroxicam, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Piroxicam.
How long after taking Piroxicam can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Piroxicam has totally cleared your system before taking weed, even in small quantities.
Overdose on Piroxicam and weed
In the case of Overdose on Piroxicam or if you are worried after mixing Piroxicam and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Piroxicam or mixed weed with Piroxicam then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Piroxicam and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Piroxicam and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Piroxicam and weed. These individuals may not realize that there are side effects and consequences to consuming both Piroxicam, marijuana and a range of antidepressants.
Studies on weed, Piroxicam and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Piroxicam
A lot of people suffer from depression caused by weed and Piroxicam. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Piroxicam and weed
Quitting weed to take Piroxicam
Medical professionals say an individual prescribed or taking Piroxicam should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Piroxicam.
A person beginning to use Piroxicam should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Piroxicam can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Piroxicam may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Piroxicam and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Piroxicam or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Piroxicam from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Piroxicam.
If you take Piroxicam, and also drink Alcohol or MDMA, you can research the effects of Piroxicam and Alcohol , Piroxicam and Cocaine as well as Piroxicam and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
Piroxicam and Weed
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