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What happens when you mix Mercaptopurine and alcohol
Side effects of mixing alcohol and Mercaptopurine can include
Shortness of breath
Interestingly, it is impossible to tell what effect Mercaptopurine and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Mercaptopurine and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Mercaptopurine and Alcohol it’s imperative that you head to your local emergency room.
Alcohol and Mercaptopurine
Alcohol and Mercaptopurine creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and Mercaptopurine and even mixing a small amount of Mercaptopurine and alcohol is not recommended.
The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with Mercaptopurine this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Alcohol and Mercaptopurine affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Mercaptopurine and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how Mercaptopurine and alcohol is going to affect an individual before they take it.
Taking Mercaptopurine and alcohol together
People who take alcohol and Mercaptopurine together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Mercaptopurine and alcohol depend on whether you consume more alcohol in relation to Mercaptopurine or more Mercaptopurine in relation to alcohol.
The use of significantly more Mercaptopurine with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both alcohol and Mercaptopurine may experience effects such as:
reduced motor reflexes from alcohol and Mercaptopurine
dizziness from alcohol and Mercaptopurine
nausea and vomiting of the Mercaptopurine
Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and Mercaptopurine leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death. Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.
Alcohol Vs Mercaptopurine
Taking Mercaptopurine in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Mercaptopurine and alcohol may have difficulty forming new memories. With alcohol vs Mercaptopurine in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Mercaptopurine when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Mercaptopurine and alcohol can lead to permanent changes in the brain. Stopping Alcohol Consumption can cause alcohol withdrawals while stopping Mercaptopurine can also cause withdrawals.
Mercaptopurine Vs alcohol
Studies investigating the effects of drugs such as Mercaptopurine and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Mercaptopurine and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and Mercaptopurine together.
When a small to medium amount of alcohol is combined with Mercaptopurine, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as Mercaptopurine.
Mercaptopurine and alcohol
Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. Specifically it is used to treat acute lymphocytic leukemia (ALL), acute promyelocytic leukemia (APL), Crohn’s disease, and ulcerative colitis. For acute lymphocytic leukemia it is generally used with methotrexate. It is taken by mouth.
Common side effects include bone marrow suppression, liver toxicity, vomiting, and loss of appetite. Other serious side effects include an increased risk of future cancer and pancreatitis. Those with a genetic deficiency in thiopurine S-methyltransferase are at higher risk of side effects. Use in pregnancy may harm the baby. Mercaptopurine
is in the thiopurine and antimetabolite family of medications.
How long after taking Mercaptopurine can I drink alcohol
To avoid any residual toxicity it is advisable to wait until the Mercaptopurine has totally cleared your system before drinking alcohol, even in small quantities.
Overdose on Mercaptopurine and alcohol
Overdose on Mercaptopurine and alcohol is alarmingly common and can often be fatal. In the case of Overdose on Mercaptopurine or if you are worried after mixing Mercaptopurine and alcohol call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Mercaptopurine or mixed alcohol with Mercaptopurine then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Mercaptopurine and alcohol. The combination of alcohol and Mercaptopurine increases the likelihood that a person would be transferred to intensive care.
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