Cefotaxime and Weed
Edited by Hugh Soames
Advertising: We may earn a commission if you buy anything via our advertising or external links
Cefotaxime and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Cefotaxime. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Cefotaxime and Weed.
Mixing Cefotaxime and Weed
Cefotaxime is an antibiotic used to treat a number of bacterial infections in human, other animals and plant tissue culture. Specifically in humans it is used to treat joint infections, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, sepsis, gonorrhea, and cellulitis. It is given either by injection into a vein or muscle.
Common side effects include nausea, allergic reactions, and inflammation at the site of injection. Another side effect may include Clostridium difficile diarrhea. It is not recommended in people who have had previous anaphylaxis to a penicillin. It is relatively safe for use during pregnancy and breastfeeding. It is in the third-generation cephalosporin family of medications and works by interfering with the bacteria’s cell wall.
Cefotaxime was discovered in 1976, and came into commercial use in 1980. It is on the World Health Organization’s List of Essential Medicines. It is available as a generic medication.
It is a broad-spectrum antibiotic with activity against numerous gram-positive and gram-negative bacteria.
Given its broad spectrum of activity, cefotaxime is used for a variety of infections, including:
Although cefotaxime has demonstrated efficacy in these infections, it is not necessarily considered to be the first-line agent. In meningitis, cefotaxime crosses the blood–brain barrier better than cefuroxime.
As a β-lactam antibiotic in the third-generation class of cephalosporins, cefotaxime is active against numerous Gram-positive and Gram-negative bacteria, including several with resistance to classic β-lactams such as penicillin. These bacteria often manifest as infections of the lower respiratory tract, skin, central nervous system, bone, and intra-abdominal cavity. While regional susceptibilities must always be considered, cefotaxime typically is effective against these organisms (in addition to many others):
Notable organisms against which cefotaxime is not active include Pseudomonas and Enterococcus. As listed, it has modest activity against the anaerobic Bacteroides fragilis.
The following represents MIC susceptibility data for a few medically significant microorganisms:
Historically, cefotaxime has been considered to be comparable to ceftriaxone (another third-generation cephalosporin) in safety and efficacy for the treatment of bacterial meningitis, lower respiratory tract infections, skin and soft tissue infections, genitourinary tract infections, and bloodstream infections, as well as prophylaxis for abdominal surgery. The majority of these infections are caused by organisms traditionally sensitive to both cephalosporins. However, ceftriaxone has the advantage of once-daily dosing, whereas the shorter half-life of cefotaxime necessitates two or three daily doses for efficacy. Changing patterns in microbial resistance suggest cefotaxime may be suffering greater resistance than ceftriaxone, whereas the two were previously considered comparable. Considering regional microbial sensitivities is also important when choosing any antimicrobial agent for the treatment of infection.
Cefotaxime is contraindicated in patients with a known hypersensitivity to cefotaxime or other cephalosporins. Caution should be used and risks weighed against potential benefits in patients with an allergy to penicillin, due to cross-reactivity between the classes.
The most common adverse reactions experienced are:
Cefotaxime is a β-lactam antibiotic (which refers to the structural components of the drug molecule itself). As a class, β-lactams inhibit bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs). This inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) in the absence of cell wall assembly. Due to the mechanism of their attack on bacterial cell wall synthesis, β-lactams are considered to be bactericidal.
Unlike β-lactams such as penicillin and amoxicillin, which are highly susceptible to degradation by β-lactamase enzymes (produced, for example, nearly universally by S. aureus), cefotaxime boasts the additional benefit of resistance to β-lactamase degradation due to the structural configuration of the cefotaxime molecule. The syn-configuration of the methoxyimino moiety confers stability against β-lactamases. Consequently, the spectrum of activity is broadened to include several β-lactamase-producing organisms (which would otherwise be resistant to β-lactam antibiotics), as outlined below.[citation needed]
Cefotaxime, like other β-lactam antibiotics, does not only block the division of bacteria, including cyanobacteria, but also the division of cyanelles, the photosynthetic organelles of the glaucophytes, and the division of chloroplasts of bryophytes. In contrast, it has no effect on the plastids of the vascular plants. This supports the endosymbiotic theory and indicates an evolution of plastid division in land plants.
Cefotaxime is administered by intramuscular injection or intravenous infusion. As cefotaxime is metabolized to both active and inactive metabolites by the liver and largely excreted in the urine, dose adjustments may be appropriate in people with renal or hepatic impairment.
Cefotaxime is the only cephalosporin which has very low toxicity in plants, even at higher concentration (up to 500 mg/L). It is widely used to treat plant tissue infections with Gram-negative bacteria, while vancomycin is used to treat the plant tissue infections with Gram-positive bacteria.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Cefotaxime and Weed and an increase in anxiety.
Anyone mixing Cefotaxime and weed is likely to experience side effects. This happens with all medications whether weed or Cefotaxime is mixed with them. Side effects can be harmful when mixing Cefotaxime and weed. Doctors are likely to refuse a patient a Cefotaxime prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Cefotaxime and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Cefotaxime are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Cefotaxime. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Cefotaxime and Weed, dol not interact is wrong. There will always be an interaction between Cefotaxime and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Cefotaxime and Weed is Scromiting. This condition, reportedly caused by mixing Cefotaxime and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Cefotaxime and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Cefotaxime and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Cefotaxime?
The way in which the body absorbs and process Cefotaxime may be affected by weed. Therefore, the potency of the Cefotaxime may be less effective. Marijuana inhibits the metabolization of Cefotaxime. Not having the right potency of Cefotaxime means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Cefotaxime medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Cefotaxime medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Cefotaxime and Weed
Many individuals may not realize that there are side effects and consequences to mixing Cefotaxime and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Cefotaxime and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Cefotaxime and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Cefotaxime and Weed is not recommended.
Taking Cefotaxime and Weed together
People who take Cefotaxime and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Cefotaxime and weed depend on whether you consume more weed in relation to Cefotaxime or more Cefotaxime in relation to weed.
The use of significantly more weed and Cefotaxime will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Cefotaxime may experience effects such as:
- reduced motor reflexes from Cefotaxime and Weed
- dizziness from Weed and Cefotaxime
- nausea and vomiting due to Cefotaxime and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Cefotaxime leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Cefotaxime
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Cefotaxime this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Cefotaxime affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Cefotaxime and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Cefotaxime can be just as harmful and there is no way of knowing exactly how Cefotaxime and weed is going to affect an individual before they take it.
Taking Cefotaxime and weed together
People who take Cefotaxime and weed together will experience the effects of both substances. The use of significantly more Cefotaxime with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Cefotaxime may experience effects such as:
- reduced motor reflexes from Cefotaxime and weed
- dizziness from weed and Cefotaxime
- nausea and vomiting of the Cefotaxime
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Cefotaxime leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Cefotaxime
Taking Cefotaxime in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Cefotaxime and weed may have difficulty forming new memories. With weed vs Cefotaxime in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Cefotaxime when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Cefotaxime and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Cefotaxime Vs Weed
Studies investigating the effects of drugs such as Cefotaxime and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Cefotaxime and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Cefotaxime together.
When a small to medium amount of weed is combined with Cefotaxime, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Cefotaxime.
How long after taking Cefotaxime can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Cefotaxime has totally cleared your system before taking weed, even in small quantities.
Overdose on Cefotaxime and weed
In the case of Overdose on Cefotaxime or if you are worried after mixing Cefotaxime and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Cefotaxime or mixed weed with Cefotaxime then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Cefotaxime and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Cefotaxime and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Cefotaxime and weed. These individuals may not realize that there are side effects and consequences to consuming both Cefotaxime, marijuana and a range of antidepressants.
Studies on weed, Cefotaxime and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Cefotaxime
A lot of people suffer from depression caused by weed and Cefotaxime. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Cefotaxime and weed
Quitting weed to take Cefotaxime
Medical professionals say an individual prescribed or taking Cefotaxime should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Cefotaxime.
A person beginning to use Cefotaxime should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Cefotaxime can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Cefotaxime may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Cefotaxime and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Cefotaxime or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Cefotaxime from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Cefotaxime.
If you take Cefotaxime, and also drink Alcohol or MDMA, you can research the effects of Cefotaxime and Alcohol , Cefotaxime and Cocaine as well as Cefotaxime and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
Cefotaxime and Weed
Counselling for Weed Addiction; Low Cost - Qualified Therapists - Available Now - 20% Off
We may make a commission if you purchase anything via the adverts or links on this page.
Betterhelp is for anyone suffering from mental health issues. Whether you suffer from anxiety, depression, weed addiction, eating disorders, or just need someone to speak to, Betterhelp can pair you with a qualified therapist.
In the wake of the pandemic, an increasing number of people have sought out therapeutic and conseling services to help with weed cessation. Better Help has seen a massive rise in people seeking help over the last two to three years.
If you or someone you care about is smoking or ingesting a level of weed that makes their life become unmanageable, Betterhelp has counselors and therapists on hand to help for less that $90 per week.
Specializations | Burnout, Anxiety, Depression, Stress, Anger Management, Dependencies, Grief, Seasonal Depressive Disorder, Life Crisis, Smoking Cessation, Weed Cessation (among others)
Betterhelp Cost | The standard fee for BetterHelp therapy is only $60 to $90 per week or $240 to $360 per month.
Key Takeaways |
- Largest online therapy platform
- Low cost
- Good for stopping weed
- Messaging
- Live video
- Phone calls
- Live chat
- No lock in contracts
- Cancel anytime
- Licensed and accredited therapists
Discounts Available | We have negotiated a generous 20% discount for readers of our website. Press Here to get 20% Off
