Brimonidine Tartrate and Weed
Edited by Hugh Soames
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Brimonidine Tartrate and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Brimonidine Tartrate. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Brimonidine Tartrate and Weed.
Mixing Brimonidine Tartrate and Weed
Brimonidine is a medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. In rosacea it improves the redness. It is used as eye drops or applied to the skin.
Common side effects when used in the eyes include itchiness, redness, and a dry mouth. Common side effects when used on the skin include redness, burning, and headaches. More significant side effects may include allergic reactions and low blood pressure. Use in pregnancy appears to be safe. When applied to the eye it works by decreasing the amount of aqueous humor made while increasing the amount that drains from the eye. When applied to the skin it works by causing blood vessels to contract.
Brimonidine was patented in 1972 and came into medical use in 1996. It is available as a generic medication. In 2020, it was the 175th most commonly prescribed medication in the United States, with more than 3 million prescriptions.
Brimonidine is indicated for the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It is also the active ingredient of brimonidine/timolol along with timolol maleate.
A 2017 Cochrane review found insufficient evidence to determine if brimonidine slows optic nerve damage.
In 2013, the FDA approved topical application of brimonidine 0.33% gel for persistent facial redness of rosacea.
Brimonidine is an α2 adrenergic agonist.
α2 agonists, through the activation of a G protein-coupled receptor, inhibit the activity of adenylate cyclase. This reduces cAMP and hence aqueous humour production by the ciliary body.
Peripheral α2 agonist activity results in vasoconstriction of blood vessels (as opposed to central α2 agonist activity that decreases sympathetic tone, as can be seen by the medication clonidine). This vasoconstriction may explain the acute reduction in aqueous humor flow. The increased uveoscleral outflow from prolonged use may be explained by increased prostaglandin release due to α adrenergic stimulation. This may lead to relaxed ciliary muscle and increased uveoscleral outflow.
It is sold under the brand names Alphagan, Alphagan-P, Mirvaso, Lumify, Brymont, and others.
In July 2018, Bausch and Lomb began to market over the counter (OTC) eye drops, using brimonidine’s tartrate formulation in a concentration of 0.025%, as an ophthalmic vasoconstrictor under the brand name Lumify. Intended to relieve redness in the sclerae of the eyes for periods of up to eight hours at a time through its vasoconstrictive effects, Lumify was marketed as an alternative to Visine, the brand of tetrahydrozoline hydrochloride solution most commonly used for that purpose.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Brimonidine Tartrate and Weed and an increase in anxiety.
Anyone mixing Brimonidine Tartrate and weed is likely to experience side effects. This happens with all medications whether weed or Brimonidine Tartrate is mixed with them. Side effects can be harmful when mixing Brimonidine Tartrate and weed. Doctors are likely to refuse a patient a Brimonidine Tartrate prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Brimonidine Tartrate and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Brimonidine Tartrate are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Brimonidine Tartrate. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Brimonidine Tartrate and Weed, dol not interact is wrong. There will always be an interaction between Brimonidine Tartrate and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Brimonidine Tartrate and Weed is Scromiting. This condition, reportedly caused by mixing Brimonidine Tartrate and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Brimonidine Tartrate and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Brimonidine Tartrate and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Brimonidine Tartrate?
The way in which the body absorbs and process Brimonidine Tartrate may be affected by weed. Therefore, the potency of the Brimonidine Tartrate may be less effective. Marijuana inhibits the metabolization of Brimonidine Tartrate. Not having the right potency of Brimonidine Tartrate means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Brimonidine Tartrate medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Brimonidine Tartrate medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Brimonidine Tartrate and Weed
Many individuals may not realize that there are side effects and consequences to mixing Brimonidine Tartrate and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Brimonidine Tartrate and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Brimonidine Tartrate and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Brimonidine Tartrate and Weed is not recommended.
Taking Brimonidine Tartrate and Weed together
People who take Brimonidine Tartrate and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Brimonidine Tartrate and weed depend on whether you consume more weed in relation to Brimonidine Tartrate or more Brimonidine Tartrate in relation to weed.
The use of significantly more weed and Brimonidine Tartrate will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Brimonidine Tartrate may experience effects such as:
- reduced motor reflexes from Brimonidine Tartrate and Weed
- dizziness from Weed and Brimonidine Tartrate
- nausea and vomiting due to Brimonidine Tartrate and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Brimonidine Tartrate leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Brimonidine Tartrate
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Brimonidine Tartrate this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Brimonidine Tartrate affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Brimonidine Tartrate and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Brimonidine Tartrate can be just as harmful and there is no way of knowing exactly how Brimonidine Tartrate and weed is going to affect an individual before they take it.
Taking Brimonidine Tartrate and weed together
People who take Brimonidine Tartrate and weed together will experience the effects of both substances. The use of significantly more Brimonidine Tartrate with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Brimonidine Tartrate may experience effects such as:
- reduced motor reflexes from Brimonidine Tartrate and weed
- dizziness from weed and Brimonidine Tartrate
- nausea and vomiting of the Brimonidine Tartrate
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Brimonidine Tartrate leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Brimonidine Tartrate
Taking Brimonidine Tartrate in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Brimonidine Tartrate and weed may have difficulty forming new memories. With weed vs Brimonidine Tartrate in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Brimonidine Tartrate when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Brimonidine Tartrate and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Brimonidine Tartrate Vs Weed
Studies investigating the effects of drugs such as Brimonidine Tartrate and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Brimonidine Tartrate and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Brimonidine Tartrate together.
When a small to medium amount of weed is combined with Brimonidine Tartrate, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Brimonidine Tartrate.
How long after taking Brimonidine Tartrate can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Brimonidine Tartrate has totally cleared your system before taking weed, even in small quantities.
Overdose on Brimonidine Tartrate and weed
In the case of Overdose on Brimonidine Tartrate or if you are worried after mixing Brimonidine Tartrate and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Brimonidine Tartrate or mixed weed with Brimonidine Tartrate then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Brimonidine Tartrate and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Brimonidine Tartrate and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Brimonidine Tartrate and weed. These individuals may not realize that there are side effects and consequences to consuming both Brimonidine Tartrate, marijuana and a range of antidepressants.
Studies on weed, Brimonidine Tartrate and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Brimonidine Tartrate
A lot of people suffer from depression caused by weed and Brimonidine Tartrate. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Brimonidine Tartrate and weed
Quitting weed to take Brimonidine Tartrate
Medical professionals say an individual prescribed or taking Brimonidine Tartrate should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Brimonidine Tartrate.
A person beginning to use Brimonidine Tartrate should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Brimonidine Tartrate can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Brimonidine Tartrate may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Brimonidine Tartrate and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Brimonidine Tartrate or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Brimonidine Tartrate from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Brimonidine Tartrate.
If you take Brimonidine Tartrate, and also drink Alcohol or MDMA, you can research the effects of Brimonidine Tartrate and Alcohol , Brimonidine Tartrate and Cocaine as well as Brimonidine Tartrate and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
Brimonidine Tartrate and Weed
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