Blincyto and Weed

Edited by Hugh Soames
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Blincyto and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Blincyto. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Blincyto and Weed.
Mixing Blincyto and Weed
Blinatumomab, sold under the brand name Blincyto, is a biopharmaceutical medication used as a second-line treatment for Philadelphia chromosome-negative relapsed or refractory acute lymphoblastic leukemia. It belongs to a class of constructed monoclonal antibodies, bi-specific T-cell engagers (BiTEs), that exert action selectively and direct the human immune system to act against tumor cells. Blinatumomab specifically targets the CD19 antigen present on B cells. In December 2014, it was approved by the US Food and Drug Administration under the accelerated approval program; marketing authorization depended on the outcome of clinical trials that were ongoing at the time of approval.
Blinatumomab is given as a continuous IV infusion for 28 consecutive days per cycle. The dose depends on a patient’s actual body weight. Patients weighing over 45 kg should receive fixed doses while patients weighing less than 45 kg should receive doses based on their estimated body surface area.
Blinatumomab was originally approved to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia in adults and children. It is approved by the US Food and Drug Administration (FDA) for B-cell precursor acute lymphoblastic leukemia (ALL) in first or second complete remission with minimal residual disease greater than or equal to 0.1% as well as relapsed or refractory B-cell precursor ALL.
Blinatumomab is a bispecific T-cell engager (BiTE). It enables a patient’s T cells to recognize malignant B cells. A molecule of blinatumomab combines two binding sites: a CD3 site for T cells and a CD19 site for the target B cells. CD3 is part of the T cell receptor. The drug works by linking these two cell types and activating the T cell to exert cytotoxic activity on the target cell. CD3 and CD19 are expressed in both pediatric and adult patients, making blinatumomab a potential therapeutic option for both pediatric and adult populations.
The drug (originally known as MT103) was developed by a German-American company Micromet, Inc. in cooperation with Lonza; In 2012, Micromet was purchased by Amgen, which furthered the drug’s clinical trials.
In July 2014, the FDA granted breakthrough therapy status to blinatumomab for the treatment of acute lymphoblastic leukemia (ALL). In October 2014, Amgen’s Biologics License Application for blinatumomab was granted priority review designation by the FDA, thus establishing a deadline of 19 May 2015, for completion of the FDA review process.
On 3 December 2014, the drug was approved for use in the United States to treat Philadelphia chromosome-negative relapsed or refractory acute lymphoblastic leukemia under the FDA’s accelerated approval program; marketing authorization depended on the outcome of clinical trials that were ongoing at the time of approval.
When blinatumomab was approved, Amgen announced that the price for the drug would be US$178,000 per year, which made it the most expensive cancer drug on the market. Merck’s pembrolizumab was priced at US$150,000 per year when it launched (in September 2014). At the time of initial approval, only about 1,000 patients in the US had an indication for blinatumomab.
Peter Bach, director of the Center for Health Policy and Outcomes at Memorial Sloan-Kettering Cancer Center, calculated that according to “value-based pricing,” assuming that the value of a year of life is US$121,000 with a 15% “toxicity discount,” the market price of blinatumomab should be US$12,612 a month, compared to the market price of US$64,260 a month. A representative of Amgen said, “The price of Blincyto reflects the significant clinical, economic and humanistic value of the product to patients and the health-care system. The price also reflects the complexity of developing, manufacturing and reliably supplying innovative biologic medicines.”
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Blincyto and Weed and an increase in anxiety.
Anyone mixing Blincyto and weed is likely to experience side effects. This happens with all medications whether weed or Blincyto is mixed with them. Side effects can be harmful when mixing Blincyto and weed. Doctors are likely to refuse a patient a Blincyto prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Blincyto and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Blincyto are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Blincyto. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Blincyto and Weed, dol not interact is wrong. There will always be an interaction between Blincyto and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Blincyto and Weed is Scromiting. This condition, reportedly caused by mixing Blincyto and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Blincyto and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Blincyto and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Blincyto?
The way in which the body absorbs and process Blincyto may be affected by weed. Therefore, the potency of the Blincyto may be less effective. Marijuana inhibits the metabolization of Blincyto. Not having the right potency of Blincyto means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Blincyto medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Blincyto medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Blincyto and Weed
Many individuals may not realize that there are side effects and consequences to mixing Blincyto and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Blincyto and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Blincyto and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Blincyto and Weed is not recommended.
Taking Blincyto and Weed together
People who take Blincyto and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Blincyto and weed depend on whether you consume more weed in relation to Blincyto or more Blincyto in relation to weed.
The use of significantly more weed and Blincyto will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Blincyto may experience effects such as:
- reduced motor reflexes from Blincyto and Weed
- dizziness from Weed and Blincyto
- nausea and vomiting due to Blincyto and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Blincyto leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Blincyto
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Blincyto this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Blincyto affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Blincyto and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Blincyto can be just as harmful and there is no way of knowing exactly how Blincyto and weed is going to affect an individual before they take it.
Taking Blincyto and weed together
People who take Blincyto and weed together will experience the effects of both substances. The use of significantly more Blincyto with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Blincyto may experience effects such as:
- reduced motor reflexes from Blincyto and weed
- dizziness from weed and Blincyto
- nausea and vomiting of the Blincyto
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Blincyto leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Blincyto
Taking Blincyto in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Blincyto and weed may have difficulty forming new memories. With weed vs Blincyto in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Blincyto when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Blincyto and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Blincyto Vs Weed
Studies investigating the effects of drugs such as Blincyto and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Blincyto and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Blincyto together.
When a small to medium amount of weed is combined with Blincyto, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Blincyto.
How long after taking Blincyto can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Blincyto has totally cleared your system before taking weed, even in small quantities.
Overdose on Blincyto and weed
In the case of Overdose on Blincyto or if you are worried after mixing Blincyto and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Blincyto or mixed weed with Blincyto then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Blincyto and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Blincyto and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Blincyto and weed. These individuals may not realize that there are side effects and consequences to consuming both Blincyto, marijuana and a range of antidepressants.
Studies on weed, Blincyto and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Blincyto
A lot of people suffer from depression caused by weed and Blincyto. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Blincyto and weed
Quitting weed to take Blincyto
Medical professionals say an individual prescribed or taking Blincyto should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Blincyto.
A person beginning to use Blincyto should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Blincyto can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Blincyto may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Blincyto and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Blincyto or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Blincyto from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Blincyto.
If you take Blincyto, and also drink Alcohol or MDMA, you can research the effects of Blincyto and Alcohol , Blincyto and Cocaine as well as Blincyto and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.

Blincyto and Weed
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