Besivance and Weed
Edited by Hugh Soames
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Besivance and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Besivance. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Besivance and Weed.
Mixing Besivance and Weed
Besifloxacin (INN/USAN) is a fourth-generation fluoroquinolone antibiotic. The marketed compound is besifloxacin hydrochloride.
It was developed by SSP Co. Ltd., Japan, and designated SS734. SSP licensed U.S. and European rights to SS734 for ophthalmic use to InSite Vision Incorporated (OTC Pink: INSV) in 2000. InSite Vision developed an eye drop formulation (ISV-403) and conducted preliminary clinical trials before selling the product and all rights to Bausch & Lomb in 2003.
The eye drop was approved by the United States Food and Drug Administration (FDA) on May 29, 2009, and marketed under the trade name Besivance.
Besifloxacin is a fluoroquinolone that has a broad spectrum in vitro activity against a wide range of Gram-positive and Gram-negative ocular pathogens: e.g., Corynebacterium pseudodiphtheriticum, Moraxella lacunata, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus hominis, Streptococcus mitis, Streptococcus oralis, Streptococcus pneumoniae and Streptococcus salivarius.
Besifloxacin has been found to inhibit production of pro-inflammatory cytokines in vitro.
The mechanism of action of besifloxacin involves inhibition of two enzymes which are essential for the synthesis and replication of bacterial DNA: the bacterial DNA gyrase and topoisomerase IV. Clinical trials indicated that Besifloxacin was 91% effective at eliminating the causative bacteria after five days, compared to 60% in the placebo group. This did not, however necessarily correlate with condition resolution, as bacterial presence is only a part of conjunctivitis.
Besifloxacin is indicated in the treatment of bacterial conjunctivitis caused by sensitive bacteria, as well as in the prevention of infectious complications in patients undergoing laser therapy for the treatment of cataracts. It has been approved for use in children, adults, and the elderly, with clinically proven efficacy and safety from age one and older.
Besifloxacin is available as a 0.6% ophthalmological suspension, and dosing is 3 times a day, 4 to 12 hours apart for 7 days, regardless of age or condition.
During the treatment, the most frequently reported ocular adverse reaction was the appearance of conjunctival redness (approximately 2% of patients). Other possible adverse reactions, reported in subjects treated with besifloxacin were: blurred vision, eye pain, eye irritation, eye pruritus and headache.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Besivance and Weed and an increase in anxiety.
Anyone mixing Besivance and weed is likely to experience side effects. This happens with all medications whether weed or Besivance is mixed with them. Side effects can be harmful when mixing Besivance and weed. Doctors are likely to refuse a patient a Besivance prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Besivance and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Besivance are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Besivance. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Besivance and Weed, dol not interact is wrong. There will always be an interaction between Besivance and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Besivance and Weed is Scromiting. This condition, reportedly caused by mixing Besivance and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Besivance and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Besivance and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Besivance?
The way in which the body absorbs and process Besivance may be affected by weed. Therefore, the potency of the Besivance may be less effective. Marijuana inhibits the metabolization of Besivance. Not having the right potency of Besivance means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Besivance medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Besivance medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Besivance and Weed
Many individuals may not realize that there are side effects and consequences to mixing Besivance and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Besivance and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Besivance and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Besivance and Weed is not recommended.
Taking Besivance and Weed together
People who take Besivance and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Besivance and weed depend on whether you consume more weed in relation to Besivance or more Besivance in relation to weed.
The use of significantly more weed and Besivance will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Besivance may experience effects such as:
- reduced motor reflexes from Besivance and Weed
- dizziness from Weed and Besivance
- nausea and vomiting due to Besivance and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Besivance leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Besivance
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Besivance this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Besivance affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Besivance and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Besivance can be just as harmful and there is no way of knowing exactly how Besivance and weed is going to affect an individual before they take it.
Taking Besivance and weed together
People who take Besivance and weed together will experience the effects of both substances. The use of significantly more Besivance with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Besivance may experience effects such as:
- reduced motor reflexes from Besivance and weed
- dizziness from weed and Besivance
- nausea and vomiting of the Besivance
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Besivance leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Besivance
Taking Besivance in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Besivance and weed may have difficulty forming new memories. With weed vs Besivance in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Besivance when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Besivance and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Besivance Vs Weed
Studies investigating the effects of drugs such as Besivance and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Besivance and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Besivance together.
When a small to medium amount of weed is combined with Besivance, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Besivance.
How long after taking Besivance can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Besivance has totally cleared your system before taking weed, even in small quantities.
Overdose on Besivance and weed
In the case of Overdose on Besivance or if you are worried after mixing Besivance and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Besivance or mixed weed with Besivance then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Besivance and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Besivance and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Besivance and weed. These individuals may not realize that there are side effects and consequences to consuming both Besivance, marijuana and a range of antidepressants.
Studies on weed, Besivance and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Besivance
A lot of people suffer from depression caused by weed and Besivance. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Besivance and weed
Quitting weed to take Besivance
Medical professionals say an individual prescribed or taking Besivance should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Besivance.
A person beginning to use Besivance should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Besivance can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Besivance may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Besivance and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Besivance or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Besivance from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Besivance.
If you take Besivance, and also drink Alcohol or MDMA, you can research the effects of Besivance and Alcohol , Besivance and Cocaine as well as Besivance and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
Besivance and Weed
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