Atovaquone and Weed

Edited by Hugh Soames
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Atovaquone and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Atovaquone. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Atovaquone and Weed.
Mixing Atovaquone and Weed
Atovaquone, sold under the brand name Mepron, is an antimicrobial medication for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP).
Atovaquone is a chemical compound that belongs to the class of naphthoquinones. Atovaquone is a hydroxy-1,4-naphthoquinone, an analog of both ubiquinone and lawsone.
Atovaquone is a medication used to treat or prevent:
Trimethoprim/sulfamethoxazole (TMP-SMX, Bactrim) is generally considered first-line therapy for PCP (not to be confused with sulfadiazine and pyrimethamine, which is first line for toxoplasmosis). However, atovaquone may be used in patients who cannot tolerate, or are allergic to, sulfonamide medications such as TMP-SMX. In addition, atovaquone has the advantage of not causing myelosuppression, which is an important issue in patients who have undergone bone marrow transplantation.
Atovaquone is given prophylactically to kidney transplant patients to prevent PCP in cases where Bactrim is contraindicated for the patient.
Atovaquone, as a combination preparation with proguanil, has been commercially available from GlaxoSmithKline since 2000 as Malarone for the treatment and prevention of malaria.
Preliminary research found that atovaquone could inhibit the replication of SARS-CoV-2 in vitro. Clinical trials of atovaquone for the treatment of COVID-19 are planned, and ongoing in United States in December 2021.
Atovaquone has also been found to inhibit human coronavirus OC43 and feline coronavirus in vitro.
In newer researches, atovaquone did not demonstrate evidence of enhanced SARS-CoV-2 viral clearance compared with placebo.
Atovaquone is used in livestock veterinary cases of babesiosis in cattle, especially if imidocarb resistance is a concern.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Atovaquone and Weed and an increase in anxiety.
Anyone mixing Atovaquone and weed is likely to experience side effects. This happens with all medications whether weed or Atovaquone is mixed with them. Side effects can be harmful when mixing Atovaquone and weed. Doctors are likely to refuse a patient a Atovaquone prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Atovaquone and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Atovaquone are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Atovaquone. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Atovaquone and Weed, dol not interact is wrong. There will always be an interaction between Atovaquone and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Atovaquone and Weed is Scromiting. This condition, reportedly caused by mixing Atovaquone and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Atovaquone and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Atovaquone and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Atovaquone?
The way in which the body absorbs and process Atovaquone may be affected by weed. Therefore, the potency of the Atovaquone may be less effective. Marijuana inhibits the metabolization of Atovaquone. Not having the right potency of Atovaquone means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Atovaquone medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Atovaquone medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Atovaquone and Weed
Many individuals may not realize that there are side effects and consequences to mixing Atovaquone and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Atovaquone and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Atovaquone and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Atovaquone and Weed is not recommended.
Taking Atovaquone and Weed together
People who take Atovaquone and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Atovaquone and weed depend on whether you consume more weed in relation to Atovaquone or more Atovaquone in relation to weed.
The use of significantly more weed and Atovaquone will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Atovaquone may experience effects such as:
- reduced motor reflexes from Atovaquone and Weed
- dizziness from Weed and Atovaquone
- nausea and vomiting due to Atovaquone and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Atovaquone leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Atovaquone
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Atovaquone this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Atovaquone affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Atovaquone and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Atovaquone can be just as harmful and there is no way of knowing exactly how Atovaquone and weed is going to affect an individual before they take it.
Taking Atovaquone and weed together
People who take Atovaquone and weed together will experience the effects of both substances. The use of significantly more Atovaquone with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Atovaquone may experience effects such as:
- reduced motor reflexes from Atovaquone and weed
- dizziness from weed and Atovaquone
- nausea and vomiting of the Atovaquone
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Atovaquone leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Atovaquone
Taking Atovaquone in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Atovaquone and weed may have difficulty forming new memories. With weed vs Atovaquone in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Atovaquone when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Atovaquone and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Atovaquone Vs Weed
Studies investigating the effects of drugs such as Atovaquone and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Atovaquone and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Atovaquone together.
When a small to medium amount of weed is combined with Atovaquone, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Atovaquone.
How long after taking Atovaquone can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Atovaquone has totally cleared your system before taking weed, even in small quantities.
Overdose on Atovaquone and weed
In the case of Overdose on Atovaquone or if you are worried after mixing Atovaquone and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Atovaquone or mixed weed with Atovaquone then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Atovaquone and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Atovaquone and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Atovaquone and weed. These individuals may not realize that there are side effects and consequences to consuming both Atovaquone, marijuana and a range of antidepressants.
Studies on weed, Atovaquone and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Atovaquone
A lot of people suffer from depression caused by weed and Atovaquone. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Atovaquone and weed
Quitting weed to take Atovaquone
Medical professionals say an individual prescribed or taking Atovaquone should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Atovaquone.
A person beginning to use Atovaquone should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Atovaquone can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Atovaquone may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Atovaquone and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Atovaquone or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Atovaquone from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Atovaquone.
If you take Atovaquone, and also drink Alcohol or MDMA, you can research the effects of Atovaquone and Alcohol , Atovaquone and Cocaine as well as Atovaquone and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.

Atovaquone and Weed
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