Asacol and Weed

Edited by Hugh Soames
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Asacol and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Asacol. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Asacol and Weed.
Mixing Asacol and Weed
Mesalazine, also known as mesalamine or 5-aminosalicylic acid (5-ASA), is a medication used to treat inflammatory bowel disease, including ulcerative colitis and Crohn’s disease. It is generally used for mildly to moderately severe disease. It is taken by mouth or rectally. The formulations which are taken by mouth appear to be similarly effective.
Common side effects include headache, nausea, abdominal pain, and fever. Serious side effects may include pericarditis, liver problems, and kidney problems. Use in pregnancy and breastfeeding appears safe. In people with a sulfa allergy certain formulations may result in problems. Mesalazine is an aminosalicylate and anti-inflammatory. It works by direct contact with the intestines.
Mesalazine was approved for medical use in the United States in 1987. It is on the World Health Organization’s List of Essential Medicines. It is available as a generic medication. In 2020, it was the 184th most commonly prescribed medication in the United States, with more than 2 million prescriptions.
It is used to treat inflammatory bowel disease, including ulcerative colitis and Crohn’s disease (effective only in colonic diseases). It is generally used for mildly to moderately active disease. It is taken by mouth or rectally. The formulations which are taken by mouth appear to be similarly effective.
There are no data on use in pregnant women, but the drug does cross the placenta and is excreted in breast milk. The drug should not be used in children under two years of age, people with kidney disease, or people who are allergic to aspirin.
Side effects are primarily gastrointestinal but may also include headache; GI effects include nausea, diarrhea and abdominal pain. There have been scattered reports of various problems when the oral form is used, including: problems caused by myelosuppression (leukopenia, neutropenia, agranulocytosis, aplastic anaemia, and thrombocytopenia), as well as hair loss, peripheral neuropathy, pancreatitis, liver problems, myocarditis and pericarditis, allergic and fibrotic lung reactions, lupus erythematosus-like reactions and rash (including urticaria), drug fever, interstitial nephritis and nephrotic syndrome, usually reversible on withdrawal. Very rarely, use of mesalazine has been associated with an exacerbation of the symptoms of colitis, Stevens Johnson syndrome and erythema multiforme.
Mesalazine is the active moiety of sulfasalazine, which is metabolized to sulfapyridine and mesalazine. It is also the active component of the prodrug balsalazide along with the inert carrier molecule 4-aminobenzoyl-beta-alanine. It is in the category of disease-modifying antirheumatic drugs (DMARDs) family of medications. It is unclear exactly how it works. Mesalazine is claimed to be a PPAR-γ agonist.
Exact mechanism of mesalazine is unknown, but is speculated that mesalazine decreases synthesis of prostaglandin and leukotriene, modulating the inflammatory response derived from the cyclooxygenase and lipooxygenase pathways. It appears to act locally on colonic mucosa.
Mesalazine is sold under various names including Apriso, Asacol, Asacol HD, Canasa, Delzicol, Fivasa, Lialda, Pentasa, Rowasa, and Sfrowasa.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Asacol and Weed and an increase in anxiety.
Anyone mixing Asacol and weed is likely to experience side effects. This happens with all medications whether weed or Asacol is mixed with them. Side effects can be harmful when mixing Asacol and weed. Doctors are likely to refuse a patient a Asacol prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Asacol and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Asacol are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Asacol. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Asacol and Weed, dol not interact is wrong. There will always be an interaction between Asacol and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Asacol and Weed is Scromiting. This condition, reportedly caused by mixing Asacol and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Asacol and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Asacol and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Asacol?
The way in which the body absorbs and process Asacol may be affected by weed. Therefore, the potency of the Asacol may be less effective. Marijuana inhibits the metabolization of Asacol. Not having the right potency of Asacol means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Asacol medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Asacol medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Asacol and Weed
Many individuals may not realize that there are side effects and consequences to mixing Asacol and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Asacol and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Asacol and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Asacol and Weed is not recommended.
Taking Asacol and Weed together
People who take Asacol and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Asacol and weed depend on whether you consume more weed in relation to Asacol or more Asacol in relation to weed.
The use of significantly more weed and Asacol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Asacol may experience effects such as:
- reduced motor reflexes from Asacol and Weed
- dizziness from Weed and Asacol
- nausea and vomiting due to Asacol and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Asacol leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Asacol
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Asacol this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Asacol affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Asacol and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Asacol can be just as harmful and there is no way of knowing exactly how Asacol and weed is going to affect an individual before they take it.
Taking Asacol and weed together
People who take Asacol and weed together will experience the effects of both substances. The use of significantly more Asacol with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Asacol may experience effects such as:
- reduced motor reflexes from Asacol and weed
- dizziness from weed and Asacol
- nausea and vomiting of the Asacol
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Asacol leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Asacol
Taking Asacol in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Asacol and weed may have difficulty forming new memories. With weed vs Asacol in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Asacol when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Asacol and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Asacol Vs Weed
Studies investigating the effects of drugs such as Asacol and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Asacol and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Asacol together.
When a small to medium amount of weed is combined with Asacol, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Asacol.
How long after taking Asacol can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Asacol has totally cleared your system before taking weed, even in small quantities.
Overdose on Asacol and weed
In the case of Overdose on Asacol or if you are worried after mixing Asacol and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Asacol or mixed weed with Asacol then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Asacol and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Asacol and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Asacol and weed. These individuals may not realize that there are side effects and consequences to consuming both Asacol, marijuana and a range of antidepressants.
Studies on weed, Asacol and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Asacol
A lot of people suffer from depression caused by weed and Asacol. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Asacol and weed
Quitting weed to take Asacol
Medical professionals say an individual prescribed or taking Asacol should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Asacol.
A person beginning to use Asacol should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Asacol can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Asacol may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Asacol and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Asacol or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Asacol from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Asacol.
If you take Asacol, and also drink Alcohol or MDMA, you can research the effects of Asacol and Alcohol , Asacol and Cocaine as well as Asacol and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.

Asacol and Weed
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