Argatroban and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
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What happens when you mix Argatroban and alcohol


Side effects of mixing alcohol and Argatroban can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect Argatroban and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Argatroban and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Argatroban and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and Argatroban


Alcohol and Argatroban creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and Argatroban and even mixing a small amount of Argatroban and alcohol is not recommended.


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Mixing alcohol and Argatroban


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with Argatroban this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and Argatroban affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Argatroban and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how Argatroban and alcohol is going to affect an individual before they take it.


Taking Argatroban and alcohol together


People who take alcohol and Argatroban together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Argatroban and alcohol depend on whether you consume more alcohol in relation to Argatroban or more Argatroban in relation to alcohol.


The use of significantly more Argatroban with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and Argatroban may experience effects such as:


  • reduced motor reflexes from alcohol and Argatroban
  • dizziness from alcohol and Argatroban
  • nausea and vomiting of the Argatroban


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and Argatroban leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs Argatroban


Taking Argatroban in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Argatroban and alcohol may have difficulty forming new memories. With alcohol vs Argatroban in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Argatroban when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Argatroban and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping Argatroban can also cause withdrawals.


Argatroban Vs alcohol


Studies investigating the effects of drugs such as Argatroban and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Argatroban and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and Argatroban together.


When a small to medium amount of alcohol is combined with Argatroban, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as Argatroban.


Argatroban and alcohol


Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. In 2000, argatroban was licensed by the Food and Drug Administration (FDA) for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). In 2002, it was approved for use during percutaneous coronary interventions in patients who have HIT or are at risk for developing it. In 2012, it was approved by the MHRA in the UK for anticoagulation in patients with heparin-induced thrombocytopenia Type II (HIT) who require parenteral antithrombotic therapy.

Argatroban is given intravenously and drug plasma concentrations reach steady state in 1–3 hours. Argatroban is metabolized in the liver and has a half-life of about 50 minutes. It is monitored by PTT. Because of its hepatic metabolism, it may be used in patients with renal dysfunction. (This is in contrast to lepirudin, a direct thrombin inhibitor that is primarily renally cleared).



How long after taking Argatroban can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the Argatroban has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on Argatroban and alcohol


Overdose on Argatroban and alcohol is alarmingly common and can often be fatal. In the case of Overdose on Argatroban or if you are worried after mixing Argatroban and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much Argatroban or mixed alcohol with Argatroban then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Argatroban and alcohol. The combination of alcohol and Argatroban increases the likelihood that a person would be transferred to intensive care.


If you take Argatroban, and also smoke weed or take MDMA, you can research the effects of Argatroban and weed , Argatroban and Cocaine as well as Argatroban and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

To find information on Drug rehab and addiction treatment all over the world

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If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


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