Amiloride and Alcohol

{Drug} and Alcohol

  1. Authored by Philippa Gold Edited by Hugh Soames Reviewed by Michael Por, MD
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What happens when you mix Amiloride and alcohol


Side effects of mixing alcohol and Amiloride can include


  • Dizziness
  • Sluggishness
  • Drowsiness
  • Shortness of breath
  • Itching
  • Hives
  • Palpitations
  • Respiratory Depression
  • Cardiac Arrest
  • Coma
  • Seizures
  • Death


Interestingly, it is impossible to tell what effect Amiloride and alcohol will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Amiloride and alcohol due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Amiloride and Alcohol it’s imperative that you head to your local emergency room.


Alcohol and Amiloride


Alcohol and Amiloride creates a that has different effects depending on the dose: many people feel stimulated and strengthened at low doses of alcohol and Amiloride and even mixing a small amount of Amiloride and alcohol is not recommended.


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Mixing alcohol and Amiloride


The primary effect of alcohol is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters that are excitatory. When alcohol is combined with Amiloride this primary effect is exaggerated, increasing the strain on the body with unpredictable results.


Alcohol and Amiloride affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Amiloride and alcohol have a greater adverse effect yet leading medic al recommendation is that smaller does can be just as harmful and there is no way of knowing exactly how Amiloride and alcohol is going to affect an individual before they take it.


Taking Amiloride and alcohol together


People who take alcohol and Amiloride together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Amiloride and alcohol depend on whether you consume more alcohol in relation to Amiloride or more Amiloride in relation to alcohol.


The use of significantly more Amiloride with alcohol will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.


People who take both alcohol and Amiloride may experience effects such as:


  • reduced motor reflexes from alcohol and Amiloride
  • dizziness from alcohol and Amiloride
  • nausea and vomiting of the Amiloride


Some people may also experience more euphoria, depression, irritability or all three. A combination of alcohol and Amiloride leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.  Be cautious about continuing on with your daily life as a functioning alcoholic as it can disguise some of the more serious health impacts.

Alcohol Vs Amiloride


Taking Amiloride in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Amiloride and alcohol may have difficulty forming new memories. With alcohol vs Amiloride in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Amiloride when mixed with alcohol it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Amiloride and alcohol can lead to permanent changes in the brain.  Stopping Alcohol Consumption can cause alcohol withdrawals while stopping Amiloride can also cause withdrawals.


Amiloride Vs alcohol


Studies investigating the effects of drugs such as Amiloride and alcohol have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Amiloride and alcohol are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking alcohol and Amiloride together.


When a small to medium amount of alcohol is combined with Amiloride, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much alcohol were associated with other substances such as Amiloride.


Amiloride and alcohol


Amiloride, sold under the trade name Midamor among others, is a medication typically used with other medications to treat high blood pressure or swelling due to heart failure or cirrhosis of the liver. Amiloride is classified as a potassium-sparing diuretic. Amiloride is often used together with another diuretic, such as a thiazide or loop diuretic. It is taken by mouth. Onset of action is about two hours and it lasts for about a day.

Common side effects include high blood potassium, vomiting, loss of appetite, rash, and headache. The risk of high blood potassium is greater in those with kidney problems, diabetes, and those who are older. Amiloride blocks the epithelial sodium channel (ENaC) in the late distal tubule, connecting tubule, and collecting duct of the nephron, which both reduces absorption of sodium ion from the lumen of the nephron and reduces excretion of potassium ion into the lumen.



How long after taking Amiloride can I drink alcohol


To avoid any residual toxicity it is advisable to wait until the Amiloride has totally cleared your system before drinking alcohol, even in small quantities.


Overdose on Amiloride and alcohol


Overdose on Amiloride and alcohol is alarmingly common and can often be fatal. In the case of Overdose on Amiloride or if you are worried after mixing Amiloride and alcohol call a first responder or proceed to the nearest Emergency Room immediately.


If you are worried about someone who has taken too much Amiloride or mixed alcohol with Amiloride then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Amiloride and alcohol. The combination of alcohol and Amiloride increases the likelihood that a person would be transferred to intensive care.


If you take Amiloride, and also smoke weed or take MDMA, you can research the effects of Amiloride and weed , Amiloride and Cocaine as well as Amiloride and MDMA here.


To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z

Or you could find what you are looking for in our Alcohol and Other Drugs index A to L or Alcohol and Other Drugs index M to Z or our MDMA and Other Drugs Index A to L or MDMA and Other Drugs Index M to Z. or Cocaine and Other Drugs index A to L or Cocaine and Other Drugs index M to Z

To find information on Drug rehab and addiction treatment all over the world

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If you are drinking too much alcohol it may be worth understanding if you are suffering from alcoholism.  If you are please consider reaching out for help.


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