Amevive and Weed
Edited by Hugh Soames
Advertising: We may earn a commission if you buy anything via our advertising or external links
Amevive and Weed
Most people who consume marijuana do so for its mood-altering and relaxing abilities. Weed gives people a high and allows them to relax. However, heavy consumption of weed can cause unwanted results. It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Amevive. It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Amevive and Weed.
Mixing Amevive and Weed
Alefacept is a genetically engineered immunosuppressive drug. It was sold under the brand name Amevive in Canada, the United States, Israel, Switzerland and Australia. In 2011, the manufacturers made a decision to cease promotion, manufacturing, distribution and sales of Amevive during a supply disruption. According to Astellas Pharma US, Inc., the decision to cease Amevive sales was neither the result of any specific safety concern nor the result of any FDA-mandated or voluntary product recall. On the other hand, usage of Amevive was associated with a certain risk of development systemic diseases such as malignancies. This drug was never approved for the European drug market.
Alefacept is used to control inflammation in moderate to severe psoriasis with plaque formation, where it interferes with lymphocyte activation. It is also being studied in the treatment of cutaneous T-cell lymphoma and T-cell non-Hodgkin lymphoma.
Alefacept is a fusion protein: it combines part of an antibody with a protein that blocks the growth of some types of T cells.
The mechanism of action involves dual mechanisms. Alefacept inhibits the activation of CD4 and CD8+ T cells by interfering with CD2 on the T cell membrane thereby blocking the costimulatory molecule LFA-3/CD2 interaction. Another mechanism is inducing apoptosis of memory-effector T lymphocytes. If the T cells were to become activated they would stimulate proliferation of keratinocytes resulting in the typical psoriatic symptoms. Therefore, alefacept leads to clinical improvement of moderate to severe psoriasis by blunting these reactions. Combinations of therapeutic modalities have been utilized to meet the challenge of difficult to treat psoriasis.
Alefacept is indicated for the management of patients with moderate to severe chronic plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy. The concomitant use of low-potency topical corticosteroids was permitted during the treatment phase with alefacept and does not seem to pose any additional risks.
The drug was approved based upon studies involving 1,869 patients altogether with plaques covering at least 10% of body surface. Either 7.5 mg IV or 15 mg IM once a week were applied. The long-term results (reduction of at least 75% in pretreatment PASI scores) were 14% and 21%, respectively. Additional improvements ensuing after completion of the 12-week treatment phase or after completion of a second alefacept treatment were also seen. Often the remissions were maintained for 7 to 12 months after end of treatment.
No clinical experience exists in patients under 18 years of age. The drug should therefore not be used in pediatric patients.
The standard dosage regimen is the weekly application of either 7.5 mg IV or 15 mg IM for a course of 12 weeks. The benefits and risks of repeated courses have not been explored in sufficient detail. Therapy should be conducted under the supervision of a physician experienced in the use of immunosuppressant agents.
Due to availability of better tolerated and more efficacious molecules for psoriasis, alefacept was withdrawn from use by its sponsor in 2011.
Research has found that anxiety is one of the leading symptoms created by marijuana in users, and that there is a correlation between Amevive and Weed and an increase in anxiety.
Anyone mixing Amevive and weed is likely to experience side effects. This happens with all medications whether weed or Amevive is mixed with them. Side effects can be harmful when mixing Amevive and weed. Doctors are likely to refuse a patient a Amevive prescription if the individual is a weed smoker or user. Of course, this could be due to the lack of studies and research completed on the mixing of Amevive and Weed.
Heavy, long-term weed use is harmful for people. It alters the brain’s functions and structure, and all pharmaceuticals and drugs including Amevive are designed to have an impact on the brain. There is a misplaced belief that pharmaceuticals and medication work by treating only the parts of the body affected yet this is obviously not the case in terms of Amevive. For example, simple painkiller medication does not heal the injury, it simply interrupts the brains functions to receive the pain cause by the injury. To say then that two drugs, Amevive and Weed, dol not interact is wrong. There will always be an interaction between Amevive and Weed in the brain11.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/.
One of the milder side effects of mixing Amevive and Weed is Scromiting. This condition, reportedly caused by mixing Amevive and Weed, describes a marijuana-induced condition where the user experiences episodes of violent vomiting, which are often so severe and painful that they cause the person to scream. The medical term for Scromiting by mixing Amevive and Weed is cannabinoid hyperemesis syndrome, or CHS. For these reasons, some people choose to quit smoking weed.
It was first included in scientific reports in 2004. Since then, researchers have determined that Scromiting is the result of ongoing, long-term use of marijuana—particularly when the drug contains high levels of THC, marijuana’s main psychoactive ingredient. Some experts believe that the receptors in the gut become overstimulated by THC, thus causing the repeated cycles of vomiting.
In the long run, a person can become even more depressed. There is a belief that marijuana is all-natural and not harmful to a person’s health. This is not true and Amevive and weed can cause health issues the more a person consumes it.
How does Weed effect the potency of Amevive?
The way in which the body absorbs and process Amevive may be affected by weed. Therefore, the potency of the Amevive may be less effective. Marijuana inhibits the metabolization of Amevive. Not having the right potency of Amevive means a person may either have a delay in the relief of their underlying symptoms.
A person seeking Amevive medication that uses weed should speak to their doctor. It is important the doctor knows about a patient’s weed use, so they can prescribe the right Amevive medication and strength. Or depending on level of interactions they may opt to prescribe a totally different medication. It is important for the doctor to know about their patient’s marijuana use. Weed is being legalized around the US, so doctors should be open to speaking about a patient’s use of it.
Sideffects of Amevive and Weed
Many individuals may not realize that there are side effects and consequences to mixing Amevive and Weed such as:
- Dizziness
- Sluggishness
- Drowsiness
- Shortness of breath
- Itching
- Hives
- Palpitations
- Respiratory Depression
- Cardiac Arrest
- Coma
- Seizures
- Death
Interestingly, it is impossible to tell what effect mixing this substance with Weed will have on an individual due to their own unique genetic make up and tolerance. It is never advisable to mix Amevive and Weed due to the chances of mild, moderate and severe side effects. If you are having an adverse reaction from mixing Amevive and Weed it’s imperative that you head to your local emergency room. Even mixing a small amount of Amevive and Weed is not recommended.
Taking Amevive and Weed together
People who take Amevive and Weed together will experience the effects of both substances. Technically, the specific effects and reactions that occur due to frequent use of Amevive and weed depend on whether you consume more weed in relation to Amevive or more Amevive in relation to weed.
The use of significantly more weed and Amevive will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Amevive may experience effects such as:
- reduced motor reflexes from Amevive and Weed
- dizziness from Weed and Amevive
- nausea and vomiting due to Amevive and Weed
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Amevive leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Mixing weed and Amevive
The primary effect of weed is influenced by an increase in the concentration of the inhibitory neurotransmitter GABA, which is found in the spinal cord and brain stem, and by a reduction in its effect on neuronal transmitters. When weed is combined with Amevive this primary effect is exaggerated, increasing the strain on the body with unpredictable results.
Weed and Amevive affects dopamine levels in the brain, causing the body both mental and physical distress. Larger amounts of Amevive and weed have a greater adverse effect yet leading medical recommendation is that smaller does of Amevive can be just as harmful and there is no way of knowing exactly how Amevive and weed is going to affect an individual before they take it.
Taking Amevive and weed together
People who take Amevive and weed together will experience the effects of both substances. The use of significantly more Amevive with weed will lead to sedation and lethargy, as well as the synergistic effects resulting from a mixture of the two medications.
People who take both weed and Amevive may experience effects such as:
- reduced motor reflexes from Amevive and weed
- dizziness from weed and Amevive
- nausea and vomiting of the Amevive
Some people may also experience more euphoria, depression, irritability or all three. A combination of weed and Amevive leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death.
Weed Vs Amevive
Taking Amevive in sufficient quantities increases the risk of a heart failure. Additionally, people under the influence of Amevive and weed may have difficulty forming new memories. With weed vs Amevive in an individual’s system they become confused and do not understand their environment. Due to the synergistic properties of Amevive when mixed with weed it can lead to confusion, anxiety, depression and other mental disorders. Chronic use of Amevive and weed can lead to permanent changes in the brain22.G. Lafaye, L. Karila, L. Blecha and A. Benyamina, Cannabis, cannabinoids, and health – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/.
Amevive Vs Weed
Studies investigating the effects of drugs such as Amevive and weed have shown that the potential for parasomnia (performing tasks in sleep) is dramatically increased when Amevive and weed are combined. Severe and dangerous side effects can occur when medications are mixed in the system, and sleep disorders are a common side effect of taking weed and Amevive together.
When a small to medium amount of weed is combined with Amevive, sleep disorders such as sleep apnea can occur. According to the latest data from the US Centers for Disease Control and Prevention (CDC) most ER visits and hospitalizations caused by too much weed were associated with other substances such as Amevive.
How long after taking Amevive can I smoke weed or take edibles?
To avoid any residual toxicity it is advisable to wait until the Amevive has totally cleared your system before taking weed, even in small quantities.
Overdose on Amevive and weed
In the case of Overdose on Amevive or if you are worried after mixing Amevive and weed, call a first responder or proceed to the nearest Emergency Room immediately.
If you are worried about someone who has taken too much Amevive or mixed weed with Amevive then call a first responder or take them to get immediate medical help. The best place for you or someone you care about in the case of a medical emergency is under medical supervision. Be sure to tell the medical team that there is a mix of Amevive and weed in their system.
Excessive Weed intake and result in scromiting, chs, and anxiety disorder. It is advisable to quit vaping weed if you are feeling these symptoms.
Mixing Amevive and weed and antidepressants
Weed users feeling depressed and anxious may be prescribed antidepressant medication. There are some antidepressant users who also use Amevive and weed. These individuals may not realize that there are side effects and consequences to consuming both Amevive, marijuana and a range of antidepressants.
Studies on weed, Amevive and antidepressants is almost nil. The reason for so little information on the side effects of the two is mostly down to marijuana being illegal in most places – although a number of states in the United States have legalized the drug.
Self-medicating with Weed and Amevive
A lot of people suffer from depression caused by weed and Amevive. How many? According to Anxiety and Depression Association of America (ADAA), in any given year, it is estimated that nearly 16 million adults experience depression. Unfortunately, that number is likely to be wrong due to under reporting. Many people do not report suffering from depression because they do not want to be looked at as suffering from a mental illness. The stigmas around mental health continue and people do not want to be labeled as depressed.
Potential side effects from mixing Amevive and weed
Quitting weed to take Amevive
Medical professionals say an individual prescribed or taking Amevive should not stop using weed cold turkey. Withdrawal symptoms can be significant. Heavy pot users should especially avoid going cold turkey. The side effects of withdrawal from weed include anxiety, irritability, loss of sleep, change of appetite, and depression by quitting weed cold turkey and starting to take Amevive.
A person beginning to use Amevive should cut back on weed slowly. While reducing the amount of weed use, combine it with mindfulness techniques and/or yoga. Experts stress that non-medication can greatly improve a person’s mood.
Weed and Amevive can affect a person in various ways. Different types of marijuana produce different side effects. Side effects of weed and Amevive may include:
- loss of motor skills
- poor or lack of coordination
- lowered blood pressure
- short-term memory loss
- increased heart rate
- increased blood pressure
- anxiety
- paranoia
- increased energy
- increased motivation
Mixing Amevive and weed can also produce hallucinations in users. This makes marijuana a hallucinogenic for some users. Weed creates different side effects in different people, making it a very potent drug. Now, mixing Amevive or other mental health drugs with weed can cause even more unwanted side effects.
Mixing drugs and weed conclusion
Long-term weed use can make depression and anxiety worse. In addition, using marijuana can prevent Amevive from working to their full potential33.J. D. Brown and A. G. Winterstein, Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use – PMC, PubMed Central (PMC).; Retrieved September 27, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/. Weed consumption should be reduced gradually to get the most out of prescription medication. Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with Amevive.
If you take Amevive, and also drink Alcohol or MDMA, you can research the effects of Amevive and Alcohol , Amevive and Cocaine as well as Amevive and MDMA here.
To find the effects of other drugs and weed refer to our Weed and Other Drugs Index A to L or our Weed and Other Drugs Index M-Z.
Or you could find what you are looking for in our Alcohol and Interactions with Other Drugs index A to L or Alcohol and Interactions with Other Drugs index M to Z , Cocaine and Interactions with Other Drugs index A to L or Cocaine and Interactions with Other Drugs index M to Z or our MDMA and Interactions with Other Drugs Index A to L or MDMA and Interactions with Other Drugs Index M to Z.
Amevive and Weed
Counselling for Weed Addiction; Low Cost - Qualified Therapists - Available Now - 20% Off
We may make a commission if you purchase anything via the adverts or links on this page.
Betterhelp is for anyone suffering from mental health issues. Whether you suffer from anxiety, depression, weed addiction, eating disorders, or just need someone to speak to, Betterhelp can pair you with a qualified therapist.
In the wake of the pandemic, an increasing number of people have sought out therapeutic and conseling services to help with weed cessation. Better Help has seen a massive rise in people seeking help over the last two to three years.
If you or someone you care about is smoking or ingesting a level of weed that makes their life become unmanageable, Betterhelp has counselors and therapists on hand to help for less that $90 per week.
Specializations | Burnout, Anxiety, Depression, Stress, Anger Management, Dependencies, Grief, Seasonal Depressive Disorder, Life Crisis, Smoking Cessation, Weed Cessation (among others)
Betterhelp Cost | The standard fee for BetterHelp therapy is only $60 to $90 per week or $240 to $360 per month.
Key Takeaways |
- Largest online therapy platform
- Low cost
- Good for stopping weed
- Messaging
- Live video
- Phone calls
- Live chat
- No lock in contracts
- Cancel anytime
- Licensed and accredited therapists
Discounts Available | We have negotiated a generous 20% discount for readers of our website. Press Here to get 20% Off
